A New Approach for Split Renal Function Assessment Based on 3D-Models Generated from Contrast-enhanced Multi-slice Computed Tomography (Msct) Scans and Mathematical Analysis: A Pilot Study
DOI:
https://doi.org/10.18502/keg.v3i4.2221Abstract
Introduction: Instrumental methods of examination may alter the course of treatment and patients’ management: from minimally invasive nephron-sparing procedures to radical operations. Objective:to present preliminary data on split kidney function assessment (in a kidney volume, e.g. segment) in patients with urological diseases.
Materials and methods: A prospective study was launched in aResearch Institute for Uronephrology and Reproductive Health from November, 2015 to February, 2017. 31 patients were enrolled into the study: 15 with stone kidney disease, 2 with kidney anomalies, 14 with renal tumors. Contrast-enhanced CT with 3D-models and
mathematical analysis were performed in all patients. Correlation between CT-based and renal scintigraphy-based measures of split renal function was estimated.
Results: CT-based methods for the calculation of split renal function with 3D-models showed correlation with renal scintigraphy (p<0.004, ttest). Conclusion: A new approach for split kidney function assessment based on contrast-enhanced CT with 3D-models and mathematical analysis allows for both acquiring detailed data on clinical anatomy and evaluation of renal function to promote preoperative decision-making.
References
El-Diastya M T, Gaballab G, Gadc H M, Borgb M A, Abou-Elgharc M E, Sheirc K Z and El- Diastyc T A 2016 Evaluation of CT perfusion parameters for assessment of split renal function in healthy donors The Egyptian Journal of Radiology and Nuclear Medicine 47-4 1681–88
Lin K-J, Huang J-Y and Chen Y-S 2011 Fully Automatic Region of Interest Selection in Glomerular Filtration Rate Estimation from 99mTc-DTPA Renogram Journal of Digital Imaging24(6) 1010-23
Fiev D N 2015 Virtual modelling for preoperative decision-making in kidney deseases(Moscow) pp 3-42
Wesolowski C A, Wanasundara S N, Wesolowski M J, Erbas B and Babyn P S Eur2016 J Nucl Med Mol Imaging 43: 550.
Nilsson H., Wadström J., Andersson L.‐G., Raland H. and Magnusson A. Measuring split renal function in renal donors: can computed tomography replace renography? Acta Radiologica 45-4, pp. 474 – 480
Alyaev Yu G et al 2014 3D technology for kidney surgery: from virtual to real surgeryedP V Glybochko and Yu G Alyaev(Moscow: GEOTAR)pp 5-280
Veenboer, P. W., Hobbelink, M. G. G., Ruud Bosch, J. L. H., Dik, P., van Asbeck, F. W. A., Beek, F. J. A. and de Kort 2015 Diagnostic accuracy of Tc-99m DMSA scintigraphy and renal ultrasonography for detecting renal scarring and relative function in patients with spinal dysraphism. Neurourol. Urodynam.,34: 513–518.
Kumar K, Ahmad A, Kumar S, Choudhry V, Kumar R, Singh T M and Muzaffar M A 2015 Evaluation of renal histopathological changes, as a predictor of recoverability of renal function following pyeloplasty for ureteropelvic junction obstruction Nephro Urol Mon. 7(4): e28051.
Torimoto I, Takebayashi S, Sekikawa Z, Teranishi J, Uchida K and Inoue T 2015 Renal perfusional cortex volume for arterial input function measured by semiautomatic segmentation technique using MDCT angiographic data with 0.5-mm collimation AJR Am J Roentgenol. 204(1):98-104.