Treatment of Sepsis in pregnancy, Childbirth and the Puerperium: Update According to New Evidence


Introduction: Sepsis is a pathology that occurs due to a serious infectious process that can lead to death. It is characterized by organic and biochemical changes that determine an exaggerated response of the organism to infection. This infectious process can start anywhere in the body, subsequently causing bacteremia, systemic invasion through the blood, causing failure of multiple organs, and may even lead to the death of the person. Objective: The objective of this work is to describe the management of this pathology, according to the best evidence and above all updated. Methodology: Virtual libraries and scientific information search engines have been used to find the best available and most up-to-date evidence, and to meet the proposed inclusion criteria, in this research process, evidence and recommendations with a high level and scientific support in English or Spanish were used. of the last years. Results: 36 scientific articles were evaluated, such as clinical practice guides, systematic reviews, meta-analyzes, clinical trials, among others, which describes the most current management in a protocolized way. Discussion: Sepsis as a pathology increases maternal and perinatal morbidity and mortality and represents the third cause of maternal death worldwide and at the national level, knowing its proper management will help improve your prognosis and recovery. Conclusion: Since the complications of sepsis can produce multi-organ failure that will compromise maternal and perinatal health, knowledge of the updated management of this pathology is essential.

Keywords: sepsis, septic shock, infection.


Introducción: La sepsis es una patología que se presenta por un proceso infeccioso grave que puede llevar a la muerte, se caracteriza por alteraciones orgánicas y bioquímicas que determinan una respuesta exagerada del organismo a la infección. Este proceso infeccioso puede iniciarse en cualquier sitio del cuerpo, provocar posteriormente bacteriemia, invasión sistémica a través de la sangre, causando falla de múltiples órganos, y pudiendo inclusive llevar al fallecimiento de la persona. Objetivo: El objetivo de este trabajo es describir el manejo de esta patología, de acuerdo a la mejor evidencia y sobre todo actualizada. Metodología:  Se ha utilizado bibliotecas virtuales y buscadores de información científica para encontrar la mejor evidencia disponible y más actualizada, y que cumplan los criterios de inclusión propuestos, en este proceso investigativo se utilizó evidencias y recomendaciones con un alto nivel y respaldo científico en idioma inglés o español de los últimos años. Resultados: Se evaluaron 36 artículos científicos como guías de práctica clínica, revisiones sistemáticas, metaanálisis, ensayos clínicos, entre otros, que describe en forma protocolizada el manejo más actual. Discusión: La sepsis como patología aumenta la morbimortalidad materna y perinatal y representa la tercera causa de muerte materna a nivel mundial y a nivel nacional conocer su manejo adecuado ayudará a mejorar su pronóstico y su recuperación. Conclusiones: Debido que las complicaciones de la sepsis pueden producir falla multiorgánica que comprometerá la salud materna y perinatal, es fundamental el conocimiento del manejo actualizado de esta patología.

Palabras clave: sepsis, choque séptico, infección.

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