Topical Application of Platelet-Rich Fibrin Liquid as a Novel and Minimally Invasive Treatment for Post-Gingival Depigmentation: A Case Report


Background: Gingival depigmentation is a common perio–esthetic surgery which results in extensive open wounds, discomfort and increased risk of infection. Cellulosebased periodontal dressing (CBP) can protect the wound, has less toxicity than Coe-Pak but no curative effect. Platelet-rich fibrin (PRF) membrane has been shown to accelerate wound healing after gingival depigmentation, but it requires suturing which causes patient discomfort. A simple and minimally invasive technique is needed to optimize the use of PRF which is convenient for both the operator and the patient.

Objective: To investigate post-gingival depigmentation outcome – wound healing, pain and post-surgical complaint – after PRF liquid application compared to CBP.

Case Report: A 24-year-old male presented with a complaint of blackish gum that affected his self-confidence. The patient had a history of smoking for the last five years. Gingival depigmentation was carried out using a scalpel followed by the application of CBP (right) and PRF liquid (left). Evaluation was done using the Visual Analogue Scale (VAS) and the Healing Index (HI) on days 3, 7 and 14 after depigmentation, followed by evaluation using the Adobe Photoshop CS2.

Results: On day 3, the PRF HI was higher than that of the CBP. No postoperative complaint in the PRF group and the VAS score was similar.

Conclusion: The results suggest that PRF liquid provides better post-gingival depigmentation healing than CBP on the third day post treatment. Furthermore, utilization of PRF liquid is expected to be an alternative for minimally invasive open wounds management especially post-gingival depigmentation.

Keywords: gingival pigmentation, platelet-rich fibrin liquid, cellulose-based periodontal dressing, wound healing, case report

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