Download fulltext HTML
Eka Satya, D., Thahir, H., Oktawati, S., Puspita Sari, N., & Tjokro, J. (2022). Efficacy of Platelet-Rich Fibrin as Regenerative Periodontal Tissue in Chronic Periodontitis: A Case Report. KnE Medicine, 2(1), 42-53. https://doi.org/10.18502/kme.v2i1.10836

https://doi.org/10.18502/kme.v2i1.10836

statistics

  • 282 Abstract Views
  • 251 PDF Views
  • 0 HTML Views

authors

  • Dian Eka Satya

    Dian Eka Satya

    Periodontology Specialist Educational Program, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
  • Hasanuddin Thahir

    Hasanuddin Thahir

    Periodontology Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
  • Sri Oktawati

    Sri Oktawati

    Periodontology Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
  • Nuraini Puspita Sari

    Nuraini Puspita Sari

    Periodontology Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
  • Jennifer Tjokro

    Jennifer Tjokro

    Periodontology Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia

Published Date

  • Apr 25, 2022

Efficacy of Platelet-Rich Fibrin as Regenerative Periodontal Tissue in Chronic Periodontitis: A Case Report

KnE Medicine / The International Online Seminar Series on Periodontology in conjunction with Scientific Seminar / Pages 42-53

Abstract

Background: One of the pertinent challenges the periodontists face today is the regeneration of periodontal tissue because of its complex structure. Periodontal tissue damage is characterized by bone and soft tissue loss. At present, one of the recommended materials for regeneration is PRF or platelet-rich fibrin. It is a regeneration material containing growth factors, prepared from the patient’s own blood, that can be used as a membrane.


Objective: To see the efficacy of healing periodontal tissue using the addition of PRF.


Method: A 31-year-old woman presented to the Department of Periodontology of Hasanuddin University Dental and Oral Hospital with the chief complaint of elongated teeth that often bled. Intraoral examination showed pocket depths of 6 mm and 5 mm in teeth 32 and 42, respectively. Radiographs showed radiolucent features in lower anterior teeth with horizontal bone loss. Chronic periodontitis of 32 and 42. Therapeutic intervention included initial therapy by scaling and root planning, followed by flap operation and regenerative therapy with PRF, membrane and bone graft.


Results: One week post regenerative therapy with PRF, the clinical appearance seemed better and there was no complaint from the patient.


Conclusion: The addition of PRF to periodontal surgery as a regenerative therapy can accelerate healing in the treatment of chronic periodontitis.


Keywords: flap operation, platelet rich-fibrin, tissue regeneration

References
[1] Arunachalam M, Pulikkotil SJ, Sonia N. Platelet rich fibrin in periodontal regeneration. The Open Dentistry Journal. 2016;10(1):174–81. http://dx.doi.org/10.2174/1874210601610010174

[2] Dharmawati IA, Manuaba IBP, Thahir H et al. Pocket measurement methods in wistar rats periodontitis induced by bacteria and the installation of silk ligature: An experimental studies. International Journal of Applied Pharmaceutics. 2019;11(4):71– 4. http://dx.doi.org/10.22159/ijap.2019.v11s4.35296

[3] Thahir H, Setiawati D. Regenerative approach in the treatment of grade II furcation: A case report. Journal of Dentomaxillofacial Science. 2019;4(1):53-56.

[4] Kumar VR, Shubhashini N. Platelet rich fibrin: A new paradigm in periodontal regeneration. Cell Tissue Bank. 2013;14(3):453–63. https://doi.org/10.1007/s10561- 012-9349-6

[5] Ajwani H, Shetty S, Gopalakrishnan D et al. Comparative evaluation of platelet-rich fibrin biomaterial and open flap debridement in the treatment of two and three wall intrabony defects. Journal of International Oral Health. 2015;7(4):32–7.

[6] Borie E, Oliví DG, Orsi IA et al. Platelet-rich fibrin application in dentistry: A literature review. International Journal of Clinical and Experimental Medicine. 2015;8(5):7922– 9.

[7] Preeja C, Arun S. Platelet-rich fibrin: Its role in periodontal regeneration. Saudi Journal for Dental Research. 2014;5(2):117–22. http://dx.doi.org/10.1016/j.ksujds.2013.09.001

[8] Miron RJ, Bishara M, Choukroun J. Basics of platelet-rich fibrin therapy. Dentistry Today. 2017;36(4):74–746.

[9] Grecu AF, Reclaru L, Ardelean LC, Nica O, Ciucă EM, Ciurea ME. Platelet-rich fibrin and its emerging therapeutic benefits for musculoskeletal injury treatment. Medicina. 2019;55(5):1–12. https://doi:10.3390/medicina55050141

[10] Su NY, Chang YC. Clinical application of platelet-rich fibrin in perio-endo combined intrabony defect. Journal of Dental Sciences. 2015;10(4):462–3. https://doi:10.1016/j.jds.2015.03.005

[11] Agarwal A, Manjunath RGS, Sethi P, Shankar GS. Platelet-rich fibrin in combination with decalcified freeze-dried bone allograft for the management of mandibular degree II furcation defect: A randomised controlled clinical trial. Singapore Dental Journal. 2020;39(1):1–8. https://doi:10.1142/s2214607519500032

[12] Suwondo CI, Herawati D, Sudibyo S. Effect of advanced platelet-rich fibrin applications on periodontal regeneration in infrabony pocket treatment. Majalah Kedokteran Gigi Indonesia. 2019;4(3):154. https://doi:10.22146/majkedgiind.37414

[13] Cortese A, Pantaleo G, Borri A, Caggiano M, Amato M. Platelet-rich fibrin (PRF) in implant dentistry in combination with new bone regenerative technique in elderly patients. International Journal of Surgery Case Reports. 2016;28:52–6. https://doi:10.1016/j.ijscr.2016.09.022