Subjective Cognitive Complaints in Distant Phase After Stroke – Preliminary Study
Introduction. Subjective cognitive decline (SCD) is often reported by healthy individuals and by different clinical groups. Current data do not clearly show the relationship between SCD and cognitive functioning, but the predictors of SCD are: age, depression and sociodemographic factors. Inconclusive data also applies to
people suffering from stroke in the distal post-stroke phase. Correct identification of the causes of SCD will help to take adequate forms of psychological therapy (neuropsychological rehabilitation and/or psychotherapy).
Methodology. The aims of research was to compare the intensity and structure of SCD as well as their
determinants in healthy persons and those after stroke. In our study 193 adults participated: 118 osób without brain pathology and 75 patients who suffered stroke 2–3 years earlier. DEX-S and ProCog as methods of evaluation of SCD and cognitive assessment techniques: the Montreal Cognitive Assessment Scale (MoCA), WAIS-R subtests and intensity of depressive mood (Geriatric Depression Scale – 15) were used in the study.
Results. Patients after stroke were characterized by more severe SCD than healthy people. People in both groups likewise (low) rated one’s own long-term memory, general cognitive and executive function. It has also been shown that people after stroke have significantly lower cognitive competencies compared to healthy
individuals, but similar (low) level of depressive mood. The later part of the analysis showed that some complaints may be determined by depressive mood, others are due to the interaction of cognitive deficits and depressive mood.
Conclusion. Our results confirm the need for proper qualifications complaints in patients after stroke (in distant post-stroke phase).
Keywords: subjective cognitive decline, stroke, cognitive functioning, depression
 Jessen, F., Wolfsgruber, S., Wiese, B., et al. (2014). German Study on Aging, Cognition and Dementia in Primary Care Patients. AD dementia risk in late MCI, in early MCI, and in subjective memory impairment. Alzheimer’s & Dementia, vol. 10, pp. 76–83.
 Steward, R. (2012). Subjective cognitive impairment. Current Opinion in Psychiatry, vol. 25, pp. 445–450.
 Abdulrab, A and Heun, R. (2008). Subjective memory impairment. A review of its definitions indicates the need for a comprehensive set of standardized and validated criteria. European Psychiatry, vol. 23, no. 5, pp. 321–330.
 Martins, I., Mares, I., and Stilwell, P. (2012). How subjective are subjective language complaints. European Journal of Neurology, vol. 19, pp. 666–671.
 Chan, R. (2001). Dysexecutive symptoms among a noc-clinical sample: A study with the use of the Dysexecutive Questionnaire. British Journal of Psychology, vol. 92, pp. 551–565.
 Gerstorf, D., Siedlecki, K., Tucker-Drob, E., et al. (2008). Executive dysfunctions across adulthood: measurement properties and correlates of the DEX self-report questionnaire. Aging, Neuropsychology and Cognition, vol. 15, no. 4, pp. 424–445.
 Rabin, L., Smart, C., Crane, P., et al. (2015). Subjective cognitive decline in older adults: An overview of self-report measures used across 19 international research studies. Journal of Alzheimer’s Disease, vol. 24, no. 48, pp. 63–86.
 Uiterwijk, R., Huijts, M., Staals, J., et al. (2014). Subjective cognitive failures in patients with hypertension are related to cognitive performance and cerebral microbleeds. Hypertension, vol. 64, no. 3, pp. 653–657.
 Hohman, T., Beason-Held, L., Lamar, M., et al. (2011). Subjective cognitive complaints and longitudinal changes in memory and brain function. Neuropsychology, vol. 25, no. 1, pp. 125–130.
 Kryscio, R., Abner, E., Jicha, G., et al. (2016). Self-reported memory complaints: A comparison of demented and unimpaired outcomes. Journal of Prevention of Alzheimer’s Disease, vol. 3, no. 1, pp. 13–19.
 Perrotin, A., Mormino, E., Madison, C., et al. (2012). Subjective cognition and amyloid deposition imaging: A Pittsburgh Compound B positron emission tomography study in normal elderly individuals. Archives of Neurology, vol. 69, pp. 223–229.
 Visser, P., Verhey, F., Knoll, D., et al. (2009). Prevalence and prognostic value of CSF markers of Alzheimer’s disease pathology in patients with subjective cognitive impairment or mild cognitive impairment in the DESCRIPA study: A prospective cohort study. The Lancet Neurology, vol. 8, pp. 619–627.
 Snitz, B., Yu, L., Crane, P., et al. (2012). Subjective cognitive complaints of older adults at the population level: An item response theory analysis. Alzheimer Disease and Associated Disorders, vol. 26, no. 4, pp. 344–351.
 Gifford, K., Liu, D., Hohman, T., et al. (2015). A mutual self- and informant-report of cognitive complaint correlates with neuropathological outcomes in Mild Cognitive Impairment. PLoS ONE 2015, vol. 10, no. 11. DOI:10.1371/journal.pone.0141831
 Edmonds, E., Delano-Wood, L., Galasko, D., et al. (2014). Subjective cognitive complaints contribute to misdiagnosis of Mild Cognitive Impairment. Journal of International Neuropsychological Society, vol. 20, no. 8, pp. 836–847.
 Caramelli, P. and Beato, R. (2008). Subjective memory complaints and cognitive performance in a sample of healthy elderly. Dementia & Neuropsychologia, vol. 2, no. 1, pp. 42–45.
 Fritsch, T., McClendon, Mc., Wallendal, M., et al. (2014). Prevalence and cognitive bases of subjective memory complaints in older adults: Evidence from a community sample. Journal of Neurodegenerative Diseases. Retrieved from http://dx.doi.org/10. 1155/2014/176843
 Caracciolo, B., Gatz, M., Xu, W., et al. (2012). Differential distribution of subjective and objective cognitive impairment in the population: A nationwide twin-study. Journal of Alzheimers Disease, vol. 29, no. 2, pp. 393–403.
 Castro, P., Aquino, C., Felício, A., et al. (2016). Presence or absence of cognitive complaints in Parkinson’s disease: Mood disorder or anosognosia? Arquivos de Neuro-Psiquiatria, vol. 74, no. 6, pp. 439–444.
 Gass, C. and Apple, C. (1997). Cognitive complaints in closed-head injury: Relationship to memory test performance and emotional disturbance. Journal of Clinical and Experimental Neuropsychology, vol. 19, no. 2, pp. 290–299.
 Jamora, Ch., Young, A., and Ruff, R. (2012). Comparison of subjective cognitive complaints with neuropsychological tests in individuals with mild vs more severe traumatic brain injuries. Brain Injury, vol. 26, no. 1, pp. 36–47.
 Haley, A., Hoth, K., Gunstad, J., et al. (2009). Subjective cognitive complaints relate to white matter hyperintensities and future cognitive decline in patients with cardiovascular disease. American Journal of Geriatric Psychiatry, vol. 17, pp. 976–985.
 van Rijsbergen, M., Mark, R., de Kort, P., et al. (2013). The COMPlaints After Stroke (COMPAS) study: Protocol for a Dutch cohort study on poststroke subjective cognitive complaints. British Medical Journal Open. DOI: 10.1136/bmjopen-2013- 003599
 Nijsse, B., van Heugten, C., van Mierlo, M., et al. (2015). Psychological factors are associated with subjective cognitive complaints 2 months post-stroke. Neuropsychological Rehabilitation: An International Journal. DOI:
 Samartzis, L., Gavala, E., Zoukos, Y., et al. (2014). Perceived cognitive decline in Multiple Sclerosis impacts quality of life independently of depression. Rehabilitation Research and Practice. Retrieved from http://dx.doi.org/10.1155/2014/128751
 Kinsinger, S., Lattie, E., and Mohr, D. (2010). Relationship between depression, fatigue, subjective cognitive impairment, and objective neuropsychological functioning in patients with Multiple Sclerosis. Neuropsychology, vol. 24, pp. 573–580.
 Rentz, D., Rodriguez, M., Amariglio, R., et al. (2013). Promising developments in neuropsychological approaches for the detection of preclinical Alzheimer’s disease: A selective review. Alzheimer’s Research & Therapy, vol. 5, p. 58. Retrieved from http://alzres.com/content/5/6/58
 Steinberg, S., Negash, S., Sammel, M., et al. (2013). Subjective memory complaints, cognitive performance, and psychological factors in healthy older adults. American Journal of Alzheimers Disease and Other Dementias, vol. 28, no. 8, pp. 776–783.
 van Rijsbergen, M., Mark, R., de Kort, P., et al. (2014). Subjective cognitive complaints after stroke: A systematic review. Journal of Stroke and Cerebrovascular Diseases, vol. 23, pp. 408–420.
 Hochstenbach, J., Prigatano, G., and Mulder, T. (2005). Patients’ and relatives’ reports of disturbances 9 months after stroke: subjective changes in physical functioning, cognition, emotion, and behavior. Archives of Physical Medicine and Rehabilitation, vol. 86, pp. 1587–1593.
 Lamb, F, Anderson, J, Saling, M, et al. (2013). Predictors of subjective cognitive complaint in postacute older adult stroke patients. Archives of Physical Medicine and Rehabilitation, vol. 94, no. 9, pp. 1747–1752.
 van Rijsbergen, M., Mark, R., Kop, W., et al. (2017). The role of objective cognitive dysfunction in subjective cognitive complaints after stroke. European Journal of Neurology, vol. 24, no. 3, pp. 475–482.
 Visser-Keizer, A., Meyboom-de Jong, B., Deelman, B., et al. (2002). Subjective changes in emotion, cognition and behaviour after stroke: Factors affecting the perceptions of patients and partners. Journal of Clinical and Experimental Neuropsychology, vol. 24, pp. 1032–1045.
 Lenehan, M., Klekociuk, S., and Summers, M. (2012). Absence of a relationship between subjective memory complaint and objective memory impairment in mild cognitive impairment (MCI): Is it time to abandon subjective memory complaint as an MCI diagnostic criterion? International Psychogeriatrics, vol. 24, no. 9, pp. 1505– 1514.
 Luria, A. R. (1962). Higher Cortical Functions in Man [Высшие корковые функции человека и их нарушения при локальных поражениях мозга]. Moscow: Moscow University.
 Gu, J., Fischer, C., Saposnik, G., et al. (2013). Profile of cognitive complaints in vascular mild cognitive impairment and mild cognitive impairment. Neurology. Retrieved from http://dx.doi.org/10.1155/2013/865827
 Prigatano, G. and Schacter, D. (eds.) (1991). Awareness of Deficit After Brain Injury. Clinical and Theoretical Issues. New York: Oxford: Oxford University Press.
 Ávila-Villanueva, M., Rebollo-Vázquez, A., Ruiz-Sánchez de León, J., et al. (2016). Clinical relevance of specific cognitive complaints in determining mild cognitive impairment from cognitively normal states in a study of healthy elderly controls. Frontiers in Aging Neuroscience. Retrieved from https://doi.org/10.3389/fnagi.2016.
 Lucki, W. (1995). A Set of Tests for Cognitive Testing of Patients with Brain Damage [Zestaw prób do badania procesów poznawczych u pacjentów z uszkodzeniami mózgu]. Warsaw: Pracownia Testów Psychologicznych.
 Frank, L., Flynn, J. A., Kleinman, L., et al. (2006). Validation of a new symptom impact questionnaire for mild to moderate cognitive impairment. International Psychogeriatrics, vol. 18, no. 1, pp. 135–149.
 Nasreddine, Z., Philips, N., Bedirian, V., et al. (2005). The Montreal Cognitive Assessment, MoCA: A brief screening tool for mild cognitive impairment. Journal of the American Geriatrics Society, vol. 53, pp. 695–699.
 Wilson, B., Alderman, N., Burgess, P., et al. (1996). Behavioral Assessment of the Dysexecutive Syndrome. Bury St. Edmunts, England: Thames Valley Test Company.
 Brzezinski, J., Gaul, M., Hornowska, E., et al. (2004). D. Wechsler’s Intelligence Scale for Adults. Revised version - renormalization WAIS-R (PL) [Skala Inteligencji D. Wechslera dla dorosłych. Wersja zrewidowana – renormalizacja WAIS-R (PL)]. Warsaw: Pracownia Testów Psychologicznych.
 Yesavage, J., Brink, T., Rose, T., et al. (1983). Development and validation of a geriatric depression screening scale: A preliminary report. Journal of Psychiatric Research, vol. 17, pp. 37–49.
 Dufouil, C., Fuhrer, R., and Alpérovitch, A. (2005). Subjective cognitive complaints and cognitive decline: Consequence or predictor? The epidemiology of vascular aging study. Journal of the American Geriatrics Society, vol. 53, pp. 616–621.
 Yates, J., Clare, L., Woods, R., et al. (2017). Subjective memory complaints, mood and MCI: A follow-up study. Aging & Mental Health, vol. 21, no. 3, pp. 313–321.
 Brigola, A., Manzini, C., Oliveira, G., et al. (2015). Subjective memory complaints associated with depression and cognitive impairment in the elderly. A systematic review. Dementia & Neuropsychologia, vol. 9, no. 1, pp. 51–57.
 Zlatar, Z., Moore, R., Palmer, B., et al. (2014). Cognitive complaints correlate with depression rather than concurrent objective cognitive impairment in the SAGE baseline sample. Journal of Geriatric Psychiatry and Neurology, vol. 27, no. 3, pp. 181– 187.
 Singh-Manoux, A., Dugravot, A., Ankri, J., et al. (2014). Subjective cognitive complaints and mortality: Does the type of complaint matter? Journal of Psychiatry Research, vol. 48, pp. 73–78.