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Ibrahim, M. H. R., Hasib, A. H., Rohmah, S. N., Abani, S., Yordan, S., & Yudaniayanti, I. S. (2017). Utilization of Honey Apis dorsata as Antiosteoporosis on Requirements of Bone Calcium Ash Density on Ovariohysterectomized White Rat (Ratus norvegicus). KnE Life Sciences, 3(6), 627-632. https://doi.org/10.18502/kls.v3i6.1191

https://doi.org/10.18502/kls.v3i6.1191

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authors

  • Muhammad Huda Ramadhan Ibrahim

    Muhammad Huda Ramadhan Ibrahim

    Student of Veterinary Medicine Faculty Airlangga University, Surabaya, 60115
  • Abdullah Hasib Hasib

    Abdullah Hasib Hasib

    Student of Veterinary Medicine Faculty Airlangga University, Surabaya, 60115
  • Siti Nur Rohmah

    Siti Nur Rohmah

    Student of Veterinary Medicine Faculty Airlangga University, Surabaya, 60115
  • Salsabilla Abani

    Salsabilla Abani

    Student of Veterinary Medicine Faculty Airlangga University, Surabaya, 60115
  • Samsi Yordan

    Samsi Yordan

    Student of Veterinary Medicine Faculty Airlangga University, Surabaya, 60115
  • Ira Sari Yudaniayanti

    Ira Sari Yudaniayanti

    Veterinary Clinical Department of Veterinary Medicine Faculty Airlangga University, Surabaya, 60115

Published Date

  • Dec 3, 2017

Utilization of Honey Apis dorsata as Antiosteoporosis on Requirements of Bone Calcium Ash Density on Ovariohysterectomized White Rat (Ratus norvegicus)

KnE Life Sciences / The Veterinary Medicine International Conference (VMIC) / Pages 627-632

Abstract

The purpose of this study was to determine the effect of honey bee Apis dorsata as anti-osteoporosis in calcium ash density (CAD) of bone in osteoporotic-induced rats. The target of this study was to know bone calcium levels after being given honey bees Apis dorsata. In this study, 35 female white rats (Ratus norvegicus) mature was used with weight 200gr. Divided into 5 groups, 2 control groups and 3 treatment groups. The negative control group (SH) was not induced by osteoporosis and was given the only aquadest of 1.5 ml/day. Whereas the positive control group was induced by osteoporosis (OH)  and was given only aquadest 1.5 ml/day. T1, T2 and T3 treatment groups were given bee honey with various doses including 1g / kg ad 1.5 ml aquadest, 2g / kg BB ad 1.5 ml aquadest and 3g / kg BB ad 1.5 ml aquadest. Then after 12 weeks, white rats were sacrificed for lumbar vertebrae. Furthermore, the sixth lumbar spine os vertebrae will be examined for calcium bone ash content. The data were obtained was analyzed using statistical analysis of variance (ANOVA) for the results of the calcium ash content data

 Keywords: Honey; Osteoporosis; CAD

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