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Javaheri, A., Kabirpour Ashkezar, S., Eftekhar, M., & Zahra Ghanadzade Tafti, S. (2021). Ovarian reserve in women with endometriosis under total cystectomy compared to partial cystectomy: A randomized clinical trial. International Journal of Reproductive BioMedicine (IJRM), 19(7), 619–624. https://doi.org/10.18502/ijrm.v19i7.9472

https://doi.org/10.18502/ijrm.v19i7.9472

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authors

  • Atiye Javaheri

    Atiye Javaheri

    Obstetrics and Gynecology Department, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  • Samane Kabirpour Ashkezar

    Samane Kabirpour Ashkezar

    Obstetrics and Gynecology Department, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
    https://orcid.org/0000-0002-1662-442X
  • Maryam Eftekhar

    Maryam Eftekhar

    Obstetrics and Gynecology Department, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  • Seiede Zahra Ghanadzade Tafti

    Seiede Zahra Ghanadzade Tafti

    Obstetrics and Gynecology Department, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Published Date

  • Aug 16, 2021

Ovarian reserve in women with endometriosis under total cystectomy compared to partial cystectomy: A randomized clinical trial

International Journal of Reproductive BioMedicine (IJRM) / International Journal of Reproductive BioMedicine (IJRM): Volume 19, Issue No. 7 / Pages 619–624

Abstract

Background: The standard procedure for ovarian endometriosis is laparoscopic excision of ovarian cysts and complete removal of the cyst capsule using the striping technique. Owing to the possibility of reducing ovarian reserve, and in some cases, the premature ovarian failure, the safety remains to be known.


Objective: To compare the ovarian reserve in women with endometriosis who underwent total cystectomy with partial cystectomy.


Materials and Methods: In this randomized clinical trial, 56 women with endometriosis who were referred to the Research and Clinical Center for Infertility and Shahid Sadoughi Hospital, Yazd, Iran between January and February 2020 were randomly assigned into two groups (n = 25/each); group I (total cystectomy) and group II (partial cystectomy). To assess the ovarian reserves, the anti-Müllerian hormone (AMH) level before and three months after surgery was measured and compared between the two groups.


Results: No significant difference was observed in the AMH levels before and after surgery (p = 0.52, p = 0.32, respectively). However, the mean reduction of AMH in total cystectomy group was significantly higher than the partial cystectomy (p = 0.001).


Conclusion: Cystectomy in women with endometriosis reduces ovarian reserve and can help maintain some ovarian reserve by performing partial instead of total cystectomy.


Key words: Anti-Müllerian hormone, Endometriosis, Cystectomy, Ovarian reserve.

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