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Hadadianpour, S., Tavana, S., Tavana, A., & Fallahian, M. (2019). Immediate dilation of a tight or stenotic cervix by intra-procedural administration of hyoscine butylbromide: A clinical trial. International Journal of Reproductive BioMedicine (IJRM), 17(4), 253–260. https://doi.org/10.18502/ijrm.v17i4.4550

https://doi.org/10.18502/ijrm.v17i4.4550

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authors

  • Shiva Hadadianpour

    Shiva Hadadianpour

    Preventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Shahrzad Tavana

    Shahrzad Tavana

    University of Texas South West (UTSW), Dallas, Texas, USA.
  • Anahita Tavana

    Anahita Tavana

    University of Texas Medical Branch (UTMB), Texas, USA.
  • Masoumeh Fallahian

    Masoumeh Fallahian

    Preventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Published Date

  • Jun 10, 2019

Immediate dilation of a tight or stenotic cervix by intra-procedural administration of hyoscine butylbromide: A clinical trial

International Journal of Reproductive BioMedicine (IJRM) / International Journal of Reproductive BioMedicine (IJRM): Volume 17, Issue No. 4 / Pages 253–260

Abstract

Background: Cervical dilation is indicated prior to performing various gynecological procedures. However, gynecologists are at times confronted with a stenotic or tight cervix, resistant to dilation. This can be problematic particularly when cervical ripening has not been attempted hours before the start of the procedure.


Objective: The objective of this study is to investigate the efficacy of administration of hyoscine butylbromide for cervical dilation for immediate dilation of the tight or stenotic cervix.


Materials and Methods: In this clinical trial study, a population of 40 women, aged 20-70 yr with stenotic cervix, evidenced by resistance to pass dilator #2 through their cervical canal were compared. Cervical patency was assessed 10 min following intracervical canal instillation of hyoscine butylbromide.


Results: Cervical width of 57.5% of patients became wider, as evidenced by passage of the number 4 Hegar dilator through the cervical canal without resistance. Independent T-tests did not reveal any statistically significant difference between the two groups based on their age. Fisher Exact test revealed a statistically significant difference between the two groups based on the prior route of delivery, with a more statistically significant response in patients who had vaginal deliveries.


Conclusion: Intra-cervical canal instillation of hyoscine butylbromide is effective in immediate dilation of the tight or stenotic cervix during intra-uterine procedures.

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