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Hossein YektaKooshali, M., Hamidi, M., Mohammad Taghi Razavi Tousi, S., & Nikokar, I. (2019). Prevalence of group B streptococcus colonization in Iranian pregnant women: A systematic review and meta-analysis. International Journal of Reproductive BioMedicine (IJRM), 16(12), 731–744. https://doi.org/10.18502/ijrm.v16i12.3679
https://doi.org/10.18502/ijrm.v16i12.3679
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- Cited by 3 articles
authors
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Mohammad Hossein YektaKooshali
No author data available.
-
Masoud Hamidi
No author data available.
-
Seyed Mohammad Taghi Razavi Tousi
No author data available.
-
Iraj Nikokar
No author data available.
Published Date
- Jan 27, 2019
Prevalence of group B streptococcus colonization in Iranian pregnant women: A systematic review and meta-analysis
Abstract
Background: Group B Streptococcus (GBS) is an important pathogen in newborns and pregnant women.
Objective: The present study was carried out to estimate the prevalence of GBS colonization in pregnant women in Iran.
Materials and Methods: This systematic review and meta-analysis was based on Preferred Reporting Items for Systematic Reviews and Meta-Analysis guideline using the national databases including Society for Information Display, Magiran, Irandoc,Iran Medex, and international databases including MEDLINE, Web of Science, Scopus,PubMed, Science-Direct, Cochrane, Embase, Elton Bryson Stephens Company, Centre for Evidence-Based Medicine, Cumulative Index to Nursing and Allied Health Literature, and Google Scholar, published by 01/30/2017. The I2 index was used to measure
heterogeneity between the studies.
Results: In a total of 667 documents, 30 (4.49%) were selected. In this study, the prevalence of GBS colonization in 10090 Iranian pregnant women was calculated as 13.65% [confidence interval (CI): 95%: 10.56–17.45]. Based on geographic region,24.63% [CI: 95%: 11.52–45.06] in the West and 8.75% [CI: 95%: 6.43–11.8] in the East were the highest and lowest areas in Iran, respectively, and were statistically significant (p = 0.001). Also, with regards to swapping sampling area, Vaginal with 11.96%, Vaginal and Rectal with 13.62%, and Anal and Vaginal with 25.63% were the least to the greatest, respectively, and were statistically significant (p = 0.001).
Conclusion: Therefore, based on the recommendation of Centers for Disease Control and Prevention as reported by the Ministry of Health and Medical education, early diagnosis, and screening of high-risk women should be done at 35–37 weeks of pregnancy.
Key words: Streptococcus agalactiae, Iran, Pregnancy, Prevalence, Female.
References
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women: survey of 11800 urine culture results. Iran J Pathol 2012; 7: 32–37.
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139–143.
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[25] YektaKooshali MH, Esmaeilpour-Bandboni M, Sharami S, Alipour Z. Survival rate and average age of the patients with breast cancer in Iran: Systematic review and metaanalysis. J Babol Univ Med Sci 2016; 18: 29–40.
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agalactiae in vaginal colonization in pregnant women using polymerase chain reaction. J Compr Ped 2014; 5: e23339.
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in southeast of Iran: incidence, serotype distribution and susceptibility to antibiotics. J Med Sci 2008; 8: 574–578.
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Perinatal Complication in Pregnant Women Referred to Alzahra Hospital. Res J Biol Sci 2008; 3: 726–728.
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colonization in Iranian pregnant women and its subsequent outcome. Int J Fertil Steril 2014; 7: 267–270.
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susceptibility and Colonization risk factors of Group B Streptococcus in genital tract of pregnant women. Med J
Mashad Univ Med Sci 2014; 57: 676–683.
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[47] Goudarzi G, Ghafarzadeh M, Shakib P, Anbari K. Culture and real-time PCR based maternal screening and antibiotic susceptibility for group B Streptococcus: an Iranian experience. Glob J Heaith Sci 2015; 7: 233–239.
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Streptococcus in Subsequent Pregnancies: A systematic review and merta-analysis. Obstet Gynecol 2015; 125: 97S.
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[2] Madzivhandila M, Adrian PV, Cutland CL, Kuwanda L, Schrag SJ, Madhi SA. Serotype distribution and invasive
potential of group B streptococcus isolates causing disease in infants and colonizing maternal-newborn dyads.
PLoS One 2011; 6: e17861.
[3] Albright CM, MacGregor C, Sutton D, Theva M, Hughes BL, Werner EF. Group B streptococci screening before repeat cesarean delivery: A cost-effectiveness analysis. Obstet Gynecol 2017; 129: 111–119.
[4] Nasri K, Chehrei A, Manavi MS. Evaluation of vaginal group B streptococcal culture results after digital vaginal
examination and its pattern of antibiotic resistance in pregnant women. Iran J Reprod Med 2013; 11: 999–1004.
[5] Haghshenas Mojaveri M, Zahedpasha Y, Asnafi N, FarhadiJ, Haddad G. A survey on the prevalence of group B streptococcus in pregnant women referred to the obstetrics and gynecology ward at babol Ayatollah Rouhani hospital. Iran J Neonatol 2014; 5: 23–27.
[6] Rahbar M, Hajia M, Mohammadzadeh M. Urinary tract infections caused by group b streptococcus in adult
women: survey of 11800 urine culture results. Iran J Pathol 2012; 7: 32–37.
[7] Malek-Jafarian M, Hosseini FS, Ahmadi AR. Pattern of infection and antibiotic activity among Streptococcus
agalactiae isolates from adults in Mashhad, Iran. RepBiochem Mol Biol 2015; 3: 89–93.
[8] Nazer MR, Rafiei Alavi E, Nazer E, Khamechi M. Prevalence of Group B Streptococcus vaginal colonization in the third trimester of pregnancy. J Shahid Sadoughi Univ Med Sci 2011; 19: 13–23 (in Persian).
[9] Illuzzi JL, Bracken MB. Duration of intrapartum prophylaxis for neonatal group B streptococcal disease: a systematic review. Obstet Gynecol 2006; 108: 1254–1265.
[10] Correa AB, Silva LG, Pinto Tde C, Oliveira IC, Fernandes FG, Costa NS, et al. The genetic diversity and phenotypic characterisation of Streptococcus agalactiae isolates from Rio de Janeiro, Brazil. Mem Inst Oswaldo Cruz 2011; 106:1002–1006.
[11] Ulett KB, Benjamin WH Jr, Zhuo F, Xiao M, Kong F, Gilbert GL, et al. Diversity of group B streptococcus serotypes causing urinary tract infection in adults. J Clin Microbiol 2009; 47: 2055–2060.
[12] Fatemi F, Chamani L, Pakzad P, Zeraati H, Rabbani H, Asgari S. Colonization rate of group B Streptococcus (GBS) in pregnant women using GBS agar medium. Acta Med Iran 2009; 47: 25–30.
[13] Engelbrecht F, Moyo SR, Maposa I, Mukesi M, Khan S. The antimicrobial susceptibility and gene based resistance of Streptococcus agalactiae (Group B Streptococcus), in pregnant women in Windhoek (Khomas region), Namibia.Med Technol SA 2017; 30: 9–14.
[14] Amirmozafari N, Mansour Ghanaei M, Sadr Nouri B, Farhadi Tooli L. Survey prevalence of group B streptococci in genital tract women in 28-37 weeks pregnancy. J Guilan Univ Med Sci 2006; 15: 91–96.
[15] Schrag S, Gorwitz R, Fultz-Butts K, Schuchat A. Prevention of perinatal group B streptococcal disease. Revised guidelines from CDC. MMWR Recomm Rep 2002; 51: 1–22.
[16] Bergeron MG, Ke D, Ménard C, François FJ, Gagnon M,Bernier M, et al. Rapid detection of group B streptococci in pregnant women at delivery. N Engl J Med 2000; 343:175–179.
[17] Javanmanesh F, Eshraghi N. Prevalence of positive rectovaginal culture for Group B streptococcus in pregnant women at 35-37 weeks of gestation. Med J Islam Repub Iran 2013; 27: 7–11.
[18] Tajbakhsh S, Norouzi Esfahani M, Emaneini M, Motamed N, Rahmani E, Gharibi S. Identification of Streptococcus agalactiae by fluorescent in situ hybridization compared to culturing and the determination of prevalence of Streptococcus agalactiae colonization among pregnant women in Bushehr, Iran. BMC Infect Dis 2013; 13: 420.
[19] Rabiei S, Arab M, Yousefi Mashouf R. Epidemiologic pattern of vaginal colonization by group B Streptococcus
in pregnant women in Hamadan, Central west of Iran. Iran J Med Sci 2006; 31: 106–108.
[20] Bidgani S, Navidifar T, Najafian M, Amin M. Comparison of group B streptococci colonization in vaginal and rectal specimens by culture method and polymerase chain reaction technique. J Chin Med Assoc 2016; 79: 141–145.
[21] Hassanzadeh P, Motamedifar M, Gharaghani MN. Carriage rate of group B streptococci in pregnant women in three teaching hospitals in Shiraz, Iran. Med Princ Pract 2011; 20:277–282.
[22] Jahed T, Shariati MK, Darabi P, Karimi A. Frequency of group B streptococcus colonization and antibiogram in
women at 35-37 weeks of gestation visited in prenatal clinic of Mahdieh Hospital in 2008. Pejouhandeh 2011; 16:
139–143.
[23] Bakhtiari R, Dallal MS, Mehrabadi J, Heidarzadeh S, Pourmand M. Evaluation of culture and PCR methods for
diagnosis of group B streptococcus carriage in Iranian pregnant women. Iran J Public Health 2012; 41: 65–70.
[24] Mansouri A, Norouzi S, YektaKooshali MH, Azami M. The relationship of maternal subclinical hypothyroidism during pregnancy and preterm birth: A systematic review and meta-analysis of cohort studies. Iran J Obstet Gynecol Infertil 2017; 19: 69–78.
[25] YektaKooshali MH, Esmaeilpour-Bandboni M, Sharami S, Alipour Z. Survival rate and average age of the patients with breast cancer in Iran: Systematic review and metaanalysis. J Babol Univ Med Sci 2016; 18: 29–40.
[26] El-Kersh TA, Al-Nuaim LA, Kharfy TA, Al-Shammary FJ, AlSaleh SS, Al-Zamel FA. Detection of genital colonization of group B streptococci during late pregnancy. Saudi Med J 2002; 23: 56–61.
[27] Jamie WE, Edwards RK, Duff P. Vaginal-perianal compared with vaginal-rectal cultures for identification of group B streptococci. Obstet Gynecol 2004; 104: 1058–1061.
[28] Yousefi Mashouf R, Mousavi SM, Rabiee S, Alikhani MY, Arabestani MR. Direct identification of Streptococcus
agalactiae in vaginal colonization in pregnant women using polymerase chain reaction. J Compr Ped 2014; 5: e23339.
[29] Bakhtiari R, Soltan Dallal M, Zaemi Yazdi J, Fallah J, Amir Mozaffari N, Pourmand M, et al. Evaluation of PCR method for diagnosis of Group B Streptococcuscarriage in pregnant women. Iran J Med Microbiol 2007; 1: 1–8.
[30] Mansouri S, Ghasami E, Shahabi Najad N. Vaginal colonization of group B streptococci during late pregnancy
in southeast of Iran: incidence, serotype distribution and susceptibility to antibiotics. J Med Sci 2008; 8: 574–578.
[31] Seddigheh AF, Reza G, Simin Z. Study on Colonization of Group B Streptococcus (GBS) and Relationship with
Perinatal Complication in Pregnant Women Referred to Alzahra Hospital. Res J Biol Sci 2008; 3: 726–728.
[32] Akhlaghi F, Hamedi A, Naderi Nasab M. Comparison of group B streptococcal colonization in the pregnant diabetic and non-diabetic women. Acta Med Iran 2009; 47: 103–108.
[33] Rohi E, Ghasemi K, Agdam FK. Incidence of nongonococcal infection in childbearing and pregnant women in ardabil. Int J Mol Clin Microbiol 2011; 1: 71–76.
[34] Shirazi M, Abbariki E, Hafizi A, Shahbazi F, Bandari M, Dastgerdy E. The prevalence of group B streptococcus
colonization in Iranian pregnant women and its subsequent outcome. Int J Fertil Steril 2014; 7: 267–270.
[35] Yasini M, Moniri R, Ghorbaali Z, Ansaripour L, Movahedinejad M, Yadegarsalehi M. Prevalence rate, Antibiotic
susceptibility and Colonization risk factors of Group B Streptococcus in genital tract of pregnant women. Med J
Mashad Univ Med Sci 2014; 57: 676–683.
[36] Fazeli Z, Alipour M, Amir Mozafari N, Ghasemi Nejad Y, Salehi Omran O, Talebjanat M. The survey of Streptococcus agalactiae carriage in pregnant women and determination of antibiotics susceptibity pattern in Amol city. Iran J Med Microbiol 2015; 9: 20–26.
[37] Moher D, Liberati A, Tetzlaff J, Altman DG, Group P.
Preferred reporting items for systematic reviews and metaanalyses: the PRISMA statement. Ann Intern Med2009;
151: 264–269.
[38] Vandenbroucke JP, Von Elm E, Altman DG, Gøtzsche PC, Mulrow CD, Pocock SJ, et al. Strengthening the reporting of observational studies in epidemiology (STROBE): explanation and elaboration. Int J Surg 2014; 12:1500–1524.
[39] Absalan M, Eslami G, Zandi H, Mosaddegh A, Vakili M, Khalili MB. Prevalence of recto-vaginal colonization of
group B streptococcus in pregnant women. J Isfahan Med Sch 2013; 30: 2367–2375.
[40] Sadeh M, Firouzi R, Derakhshandeh A, Bagher Khalili M, Kong F, Kudinha T. Molecular Characterization of
Streptococcus agalactiae Isolates From Pregnant and Non-Pregnant Women at Yazd University Hospital, Iran.
Jundishapur J Microbiol 2016; 9: e30412.
[41] Hadavand S, Ghafoorimehr F, Rajabi L, Davati A,Zafarghandi N. Frequency of Group B Streptococcal
Colonization in Pregnant Women Aged 35-37 Weeks in Clinical Centers of Shahed University, Tehran, Iran. Iran J
Pathol 2015; 10: 120–126.
[42] Sarafrazi N, Mesdaghinia E, Moniri R, Moosavi GA. Evaluation of vaginal Streptococcus hemolytic type B in pregnant women and its relationship with early neonatal infection.Feyz J Kashan Univ Med Sci 2001; 5: 22–27.
[43] Hamedi A, Akhlaghi F, Seyedi SJ, Kharazmi A. Evaluation of group B Streptococci colonization rate in pregnant women and their newborn. Acta Med Iran 2012; 50: 805–808.
[44] Habibzadeh S, Arzanlou M, Jannati E, Asmar M, Azari M, Fardiazar Z. Maternal carriage of Group B Streptococcus in Ardabil, prevalence and antimicrobial resistance. J Ardabil Univ Med Sci 2010; 10: 14–20.
[45] Namavar Jahromi B, Poorarian S, Poorbarfehee S. The prevalence and adverse effects of group B streptococcal colonization during pregnancy. Arch Iran Med 2008; 11:654–657.
[46] Abdollahi-fard S, Ghotasloo R, Zafardoost S. Study on Colonization of Group B Streptococcus (GBS) and Relationship with Perinatal Complication in Pregnant Women Referred to Alzahra Hospital. Res J Biolo Sci 2008; 3: 726–728.
[47] Goudarzi G, Ghafarzadeh M, Shakib P, Anbari K. Culture and real-time PCR based maternal screening and antibiotic susceptibility for group B Streptococcus: an Iranian experience. Glob J Heaith Sci 2015; 7: 233–239.
[48] Kalantar E. High burden of Group B Streptococcus: an invasive bacterium among pregnant women referring to Health Centers of Sanandaj, Iran. Infec Epidemiol Microbiol 2013; 1: 15–18.
[49] Tor-Udom S, Tor-Udom P, Hiriote W. The prevalence of
streptococcus agalactiae (group B) colonization in pregnant women at Thammasat Hospital. J Med Assoc Thai 2006; 89: 411–414.
[50] Lambiase A, Agangi A, Del Pezzo M, Quaglia F, Testa A, Rossano F, et al. In vitro resistance to macrolides
and clindamycin by Group B Streptococcus isolated from pregnant and nonpregnant women. Infect Dis Obstet
Gynecol 2012; 2012: 913603.
[51] Turrentine MA, Colicchia L, Hirsch E, Cheng PJ, Tam MT, Page-Ramsey SM. Risk of Recurrence of Group B
Streptococcus in Subsequent Pregnancies: A systematic review and merta-analysis. Obstet Gynecol 2015; 125: 97S.
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