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Sadat Tabatabaie, R., Dehghan, N., Mojibian, M., Hosein Lookzadeh, M., Namiranian, N., Javaheri, A., & Hajisafari, M. (2022). The relationship between postnatal hypoglycemia and umbilical artery Doppler ultrasonography in neonates with intrauterine growth restriction: A longitudinal follow-up study. International Journal of Reproductive BioMedicine (IJRM), 20(2), 137-144. https://doi.org/10.18502/ijrm.v20i2.10505

https://doi.org/10.18502/ijrm.v20i2.10505

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authors

  • Razieh Sadat Tabatabaie

    Razieh Sadat Tabatabaie

    Department of Obstetrics and Gynecology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
  • Naeime Dehghan

    Naeime Dehghan

    Department of Obstetrics and Gynecology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
  • Mahdieh Mojibian

    Mahdieh Mojibian

    Department of Obstetrics and Gynecology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
  • Mohamad Hosein Lookzadeh

    Mohamad Hosein Lookzadeh

    Mother and Newborn Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
  • Nasim Namiranian

    Nasim Namiranian

    Community and Preventive Medicine, Yazd Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
  • Atiyeh Javaheri

    Atiyeh Javaheri

    Department of Obstetrics and Gynecology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
  • Mojgan Hajisafari

    Mojgan Hajisafari

    Department of Obstetrics and Gynecology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Published Date

  • Mar 21, 2022

The relationship between postnatal hypoglycemia and umbilical artery Doppler ultrasonography in neonates with intrauterine growth restriction: A longitudinal follow-up study

International Journal of Reproductive BioMedicine (IJRM) / International Journal of Reproductive BioMedicine (IJRM): Volume 20, Issue No. 2 / Pages 137-144

Abstract

Background: Intrauterine growth restriction (IUGR) refers to fetuses with an estimated ultrasonography weight below the 10% percentile. Hypoglycemia is a major concern in neonates with IUGR.


Objective: To investigate the relationship between umbilical artery (UA) Doppler ultrasonography and neonate hypoglycemia and IUGR.


Materials and Methods: This was a longitudinal follow-up study consisting of 114 neonates (gestational age of 28-40 wk) born with IUGR in the third trimester of pregnancy at Shahid Sadoughi Hospital, Yazd, Iran between May 2016 and October 2017. The neonates were assigned into three subgroups of normal UA Doppler, absent end-diastolic flow (EDF) in UA Doppler, and reverse EDF in UA Doppler. The blood glucose of the neonates was checked one, two, three, six, 12, 24 and 48 hr after birth, and the neonates were placed in the hypoglycemia or euglycemia groups according to guidelines.


Results: Out of the 114 neonates included in the study, 75 (65.8%) had normal UA Doppler, 29 (25.4%) had absent EDF in UA Doppler, and 10 (8.8%) had reverse EDF in UA Doppler. There was a significant difference in the mean blood glucose in the first hr between the normal UA Doppler group and the reverse EDF in UA Doppler group (p < 0.01).


Conclusion: Postnatal hypoglycemia in neonates with IUGR is associated with the result of UA Doppler ultrasonography during pregnancy.


Key words: Growth restriction, Hypoglycemia, Ultrasonography Doppler, Umbilical artery.

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