Spinal myoclonus as a rare presentation of neurological disease in Sudan


Background: Spinal Myoclonus is a very rare movement disorder characterized by myoclonic involvement of the whole body. Structural lesions are usually the cause ,but in primary spinal myoclonus the etiology remain un known. Case description: We presented a 50 years old farmer from east of sudan presented with jerky movement affecting whole of his body diagnosed clinically as spinal myoclonus .      laboratory study was normal, MRI brain &cervical&dorsal Spine were normal.The patient received clonezepam with marked improvement . CONCLUSION: In any case of spinal myoclonus EEG,EMG&MRI brain &spinal cord must be done to exclude structural lesions. Clonazepam is the drug of choice with magic improvement. in segmental spinal myoclonus botulinum toxin is the best treatment .

Key words: Spinal Myoclonus ,Sudan.

1-Shibasaki, H. and Hallett, M. (2005)Electrophysiological studies of myoclonus.Muscle Nerve31: 157174.

2-Brown, P., Rothwell, J.C., Thompson, P.D. and Marsden, C.D. (1994) Propriospinal myoclonus: evidence for spinal ‘‘pattern’’ generators in humans. Mov Disord9: 571576.

3-Caviness, J.N. and Brown, P. (2004) Myoclonus: current concepts and recent advances.Lancet Neurol 3: 598607.

4-Williams, D.R., Cowey, M., Tuck, K. and Day, B.(2008) Psychogenic propriospinal myoclonus.Mov Disord23: 13121313.

5-Esposito, M., Edwards, M.J., Bhatia, K.P., Brown, P. and Cordivari, C. (2009) Idiopathic spinal myoclonus: a clinical and neurophysiological assessment of a movement disorder of uncertain origin.Mov Disord 24: 23442349.

6-van der Salm, S.M., Koelman, J.H., Henneke, S., van Rootselaar, A.F. and Tijssen, M.A. (2010) Axial jerks:a clinical spectrum ranging from propriospinal to psychogenic myoclonus.J Neurol257: 13491355.

7-Keswani, S.C., Kossoff, E.H., Krauss, G.L. and Hagerty, C. (2002) Amelioration of spinal myoclonus with levetiracetam.J Neurol Neurosurg Psychiatry 73: 457458.