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Rasmi, Y., Kheradmand, F., Nemati, M., Mollazadeh` leila, Seyyed-Mohammadzad, M., Shirpoor, A., & Khalaji, N. (2020). Distribution of Blood Groups in Patients with Angiographically Defined Coronary Artery Disease in Iranian Community. Sudan Journal of Medical Sciences (SJMS), 15(3), 217–224. https://doi.org/10.18502/sjms.v15i3.7013

https://doi.org/10.18502/sjms.v15i3.7013

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authors

  • Yousef Rasmi

    Yousef Rasmi

  • Fatemeh Kheradmand

    Fatemeh Kheradmand

    Department of Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
  • Mohadeseh Nemati

    Mohadeseh Nemati

    Department of Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
  • leila Mollazadeh`

    leila Mollazadeh`

    Department of Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
  • MirHossein Seyyed-Mohammadzad

    MirHossein Seyyed-Mohammadzad

    Department of Cardiology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
  • Alireza Shirpoor

    Alireza Shirpoor

    Department of Physiology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
  • Naser Khalaji

    Naser Khalaji

    Department of Physiology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran

Published Date

  • Sep 30, 2020

Distribution of Blood Groups in Patients with Angiographically Defined Coronary Artery Disease in Iranian Community

Sudan Journal of Medical Sciences (SJMS) / Sudan JMS: Volume 15 (2020), Issue No. 3 / Pages 217–224

Abstract

In the past, the relationship between coronary artery disease (CAD) and been studied extensively. The ABO blood group has a significant effect on homeostasis and is therefore associated with adverse cardiovascular events. This study aimed to determine the distribution of ABO blood group and rhesus (Rh) status (ABO/Rh) in patients with different severity of CAD in Iranian community. A total of 1,236 CAD patients undergoing angiography were evaluated and their ABO/Rh blood type was determined in a study center between February 2005 and December 2010. Of the 1,236 records, only 1,046 medical documents recorded the number of involved vessels. The patients were classified according to the number of significantly affected stenotic vessels into single vessel (1VD), two vessels (2VD), and three vessels (3VD) disease subgroups. A substantially different ABO/Rh blood groups distribution was seen in the examined samples (O: 29.7%, A: 39.7%, B: 22.2%, AB: 8.3%, Rh positivity: 89.2%). The ABO/Rh blood group phenotype distribution in CAD patients with 1VD, 2VD, and 3VD was as follows: 37.5%, 41.3%, and 41.5%, respectively, for group A; 24.1%, 20.5%, and 20.6%, respectively, for group B; 31.2%, 26.8%, and 30.2%, respectively, for group O; 7.1%, 11.4% and 7.7%, respectively, for group AB (p = 0.26), and 88.7%, 90.5%, and 87.6%, respectively, for Rh positivity, (p = 0.47).  In addition, no significant correlation was not found among the ABO/Rh blood group distribution and the number of vessels involved, however, according to the different distribution of ABO/Rh blood group in CAD patients and healthy population, ABO/Rh might have an unknown role in CAD patients.


Keywords: Coronary artery disease, Blood group, Stenosis, Vessel, Rhesus.

References
1. Amirzadegan A, Salarifar M, Sadeghian S, Davoodi G, Darabian C, Goodarzynejad H. Correlation between ABO blood groups, major risk factors, and coronary artery disease. International journal of cardiology. 110, 2, 2006;256-8.

2. 27th Bethesda Conference. Matching the Intensity of Risk Factor Management with the Hazard for Coronary Disease Events. September 14-15, 1995. Journal of the American College of Cardiology. 27,5,1996;957-1047.

3. Nydegger UE, Wuillemin WA, Julmy F, Meyer BJ, Carrel TP. Association of ABO histo-blood group B allele with myocardial infarction. Eur J Immunogenet. 30,3,2003;201-6.

4. Whincup PH, Cook DG, Phillips AN, Shaper AG. ABO blood group and ischaemic heart disease in British men. BMJ (Clinical research ed. 300,6741,1990;1679-82.

5. Meade TW, Cooper JA, Stirling Y, Howarth DJ, Ruddock V, Miller GJ. Factor VIII, ABO blood group and the incidence of ischaemic heart disease. British journal of haematology. 88,3,1994;601-7.

6. Etemadi A, Kamangar F, Islami F, Poustchi H, Pourshams A, Brennan P, et al. Mortality and cancer in relation to ABO blood group phenotypes in the Golestan Cohort Study. Bmc Med. 13,2015.

7. Garrison RJ, Havlik RJ, Harris RB, Feinleib M, Kannel WB, Padgett SJ. ABO blood group and cardiovacular disease: the Framingham study. Atherosclerosis. 25,2-3,1976;311-8.

8. Kanbay M, Gur G, Arslan H, Yilmaz U, Boyacioglu S. The relationship of ABO blood group, age, gender, smoking, and Helicobacter pylori infection. Dig Dis Sci. 50,7,2005;1214-7.

9. Liumbruno GM, Franchini M. Beyond immunohaematology: the role of the ABO blood group in human diseases. Blood Transfus. 11,4,2013;491-9.

10. Franchini M, Liumbruno GM. ABO blood group: old dogma, new perspectives. Clin Chem Lab Med. 51,8,2013;1545-53.

11. Franchini M, Favaloro EJ, Targher G, Lippi G. ABO blood group, hypercoagulability, and cardiovascular and cancer risk. Crit Rev Clin Lab Sci. 49,4,2012;137-49.

12. Anstee DJ. The relationship between blood groups and disease. Blood. 115,23,2010;4635-43.

13. Biancari F, Satta J, Pokela R, Juvonen T. ABO blood group distribution and severity of coronary artery disease among patients undergoing coronary artery bypass surgery in Northern Finland. Thromb Res 108,2003;195-6.

14. Pour Fathollah AA, Oodi A, Honarkaran N. Geographical distribution of ABO and Rh (D) blood groups among Iranian blood donors in the year 1361 (1982) as compared with that of the year 1380 (2001). . Blood, The Scientific Journal of Iranian Blood Transfusion Organization-research Center. 1,2004;11-7.

15. Stakisaitis D, Maksvytis A, Benetis R, Viikmaa M. [Coronary atherosclerosis and blood groups of ABO system in women (own data and review)]. Medicina (Kaunas, Lithuania). 38 ,Suppl 2,2002;230-5.

16. Chen Y, Chen C, Ke X, Xiong L, Shi Y, Li J, et al. Analysis of circulating cholesterol levels as a mediator of an association between ABO blood group and coronary heart disease. Circulation: Cardiovascular Genetics. 7,1,2014;43-8.

17. Omidi N, Khorgami MR, Effatpanah M, Khatami F, Mashhadizadeh M, Jalali A, et al. Association between ABO blood group and severity of coronary artery disease in unstable angina. ARYA atherosclerosis. 13,4,2017;172.

18. Koster T, Blann AD, Briet E, Vandenbroucke JP, Rosendaal FR. Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep-vein thrombosis. Lancet. 345,8943,1995;152-5.

19. O'Donnell J, Laffan MA. The relationship between ABO histo-blood group, factor VIII and von Willebrand factor. Transfusion medicine (Oxford, England). 11,4,2001;343-51.