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Hussein A. El Shallaly, G. E., A. B. Ibrahim, B., M. E. Salih, M., M. I. Elhajahmed, M., F. E. Mohammed, M., O. M. Daffalla, R., E. H. Yassin, R., & M. M. Ahmed, R. (2022). Histopathologic Pattern of Thyroid Disease in 1351 Thyroidectomy Patients. Sudan Journal of Medical Sciences (SJMS), 17(4), 577–588. https://doi.org/10.18502/sjms.v17i4.12555

https://doi.org/10.18502/sjms.v17i4.12555

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  • Gamal Eldin Hussein A. El Shallaly

    Gamal Eldin Hussein A. El Shallaly

    Department of Surgery, Karary University, Sudan
    https://orcid.org/0000-0002-8941-0721
  • Babiker A. B. Ibrahim

    Babiker A. B. Ibrahim

    Department of Surgery, Faculty of Medicine, Omdurman Islamic University, Sudan
  • Modather M. E. Salih

    Modather M. E. Salih

    Department of Surgery, Faculty of Medicine, Omdurman Islamic University, Sudan
  • Mohamed M. I. Elhajahmed

    Mohamed M. I. Elhajahmed

    Department of Surgery, Faculty of Medicine, Omdurman Islamic University, Sudan
  • Mohammed F. E. Mohammed

    Mohammed F. E. Mohammed

    Department of Orthopedic Surgery and Traumatology, Faculty of Medicine, Omdurman Islamic University, Sudan
  • Reem O. M. Daffalla

    Reem O. M. Daffalla

    Faculty of Medicine, Omdurman Islamic University, Sudan
  • Ruaa E. H. Yassin

    Ruaa E. H. Yassin

    Faculty of Medicine, Omdurman Islamic University, Sudan
  • Rayan M. M. Ahmed

    Rayan M. M. Ahmed

    Faculty of Medicine, Omdurman Islamic University, Sudan

Published Date

  • Dec 31, 2022

Histopathologic Pattern of Thyroid Disease in 1351 Thyroidectomy Patients

Sudan Journal of Medical Sciences (SJMS) / Sudan JMS: Volume 17 (2022), Issue No. 4 / Pages 577–588

Abstract

BackgroundThyroid disease poses a major clinical problem. Knowledge of the pattern and distribution of thyroid disease is important to establish prevention and treatment protocols. This is hampered by lack of data.
MethodsThis is a retrospective descriptive study of histopathology reports on thyroid tissue surgically excised from patients over a 10-year-period (from 2009-2020) at a major teaching hospital. Demographic data on patients included the age, gender, geographical location and ethnic origin.
Results A total of 1351 histopathological reports on thyroid patients were studied. Twenty one patients (1.6%) had thyroglossal cysts and 1330 patients (98.4%) had goiters. The mean age was 40.6 years (SD±13.25), (range 11-85years). The majority (88%) were females Most of our patients come from Khartoum (76.3%), followed by White Nile (6.4%), and El Gazira states (4.5%). The commonest ethnic groups affected were the Nuba (11.6%) and Jaalin (8%). The majority of patients (85%) had benign thyroid diseases, and only (15%) had neoplastic disease. Simple multinodular goiter (SMNG) accounted for (78.6%) of benign thyroid disease. Follicular adenoma was the commonest benign neoplasm (98%), whereas papillary carcinoma was the commonest malignant tumour (44.9%), followed by follicular carcinoma and Hurthle cell tumours (43.9%). Medullary and anaplastic carcinomas each accounted for (4.1%) of patients.
Conclusions The study identified the histopathological pattern of thyroid disease. SMNG was the commonest benign disease. Follicular and Hurtle cell carcinoma combined were almost as frequent as papillary carcinoma. Prevention of SMNG by iodinization, early detection of thyroid neoplasms, and studies on goitrogens should be activated.

Keywords:

Thyroid disease, histopathology, thyroglossal cyst, goiter thyroid cancer, thyroidectomy, Sudan, multinodular colloid goiter, thyroid adenoma

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