KnE Life Sciences | The Veterinary Medicine International Conference (VMIC) | pages: 369-377

DOI: 10.18502/kls.v3i6.1145

Iron Overload Reduces Cholestrol and Triglyceride Serum of Mice

Devi Agustin Setiawati
Department of Biochemistry and Molecular Biology Faculty of Medicine Universitas Padjadjaran, Indonesia

Mas Rizky A.A. Syamsunarno
rizky@unpad.ac.id
Department of Biochemistry and Molecular Biology Faculty of Medicine Universitas Padjadjaran Central Laboratory, Universitas Padjadjaran Department of Biology, Faculty of Mathematics and Natural Sciences, Bandung-Sumedang Street KM 21st, West Java 45363, Indonesia

Pandji Irani Fianza
Department of Internal Medicine Faculty of Medicine Universitas Padjadjaran, Pasteur Street No. 38, Bandung, West Java, Indonesia

Nur Atik
Medical Laboratorium Technologyst of Bakti Asih School of Analyst,Padasuka Atas Street No.233, Padasuka, Cimenyan, Bandung West Java, Indonesia

Neni Anggraeini
Department of Biochemistry and Molecular Biology Faculty of Medicine Universitas Padjadjaran Central Laboratory, Universitas Padjadjaran Department of Anatomy and Cell Biology, Bandung-Sumedang Street KM 21st, West Java 45363, Indonesia

Mohammad Ghozali
Central Laboratory, Universitas Padjadjaran, Indonesia

Ratu Safitri
Central Laboratory, Universitas Padjadjaran Department of Biology, Faculty of Mathematics and Natural Sciences, Bandung-Sumedang Street KM 21st, West Java 45363 7Study Program of Biotechnology, Post Graduate School, Universitas Padjadjaran, Dipati Ukur Street no. 35, Bandung West Java, Indonesia

Ramdan Panigoro
Central Laboratory, Universitas Padjadjaran, Indonesia

Abstract

Most of the case of patient with hemoglobin disorder genes need routine blood transfusion throughout their life. It leads to increase iron accumulation with liver as the main organ for iron storage. Liver is the main organ for metabolic process, including triglyceride and cholesterol. However, correlation between metabolism of triglyceride and cholesterol, and iron overload condition is remain uncertain. The purpose of this study was to investigate the effect of iron overload to triglyceride and cholesterol level in the serum of mice.

 

Keywords: iron overload; Triglyceride serum; Cholesterol Serum.

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