The Association Between Testosteron Levels and Relationship Quality in Reproductive Aged Couples
Abstract
Couple relationship is often interfered by disorder in sexual activities. Most of the problems are in women than men. One of the main factor tha contributed to sexual function are sex hormones. Sex hormones selectively responsive to sexual incentives inducing a neurochemical state that favourable to sexual response. Androgens play an important role in sexual desire, arousal, orgasm and satisfaction by interacting with receptors in the hypothalamus, together with the dopaminergic, serotoninergic and opiatergic path, and the receptor genitals. Testosterone, molecular weight of 288.41 Dalton, is one of sex steroid hormones. It is the main androgenic hormone produced by the interstitial cells (Leydig). However, testosterone is an important precursor for the production of estradiol in the target tissue. Both testosteron and estrogen may affect sexual arousal. Decrease of testoterone in men is also related to declines in sexual desire, which can be restored with testosteron administration. Therefore, adding testosteron to estrogen in sexual disorder may be benefited. However, this practice was not widely use. Furhter sutdy is needed to assess its long term side effect.
References
[1] D. Miller, Assessment and management of miscarriage, New Zealand Family Physician, 35, no. 3, (2008).
[2] I.-C. Chi, T. Agoestina, and J. Harbin, Maternal mortality at twelve teaching hospitals in Indonesia - an epidemiologic analysis, International Journal of Gynecology and Obstetrics, 19, no. 4, 259–266, (1981).
[3] R. Hasan, D. D. Baird, A. H. Herring, A. F. Olshan, M. L. Jonsson Funk, and K. E. Hartmann, Association between first-trimester vaginal bleeding and miscarriage, Obstetrics and Gynecology, 114, no. 4, 860–867, (2009).
[4] O. Hanita and A. H. Hanisah, Potential use of single measurement of serum progesterone in detecting early pregnancy failure, Malaysian Journal of Pathology,34, no. 1, 41–46, (2012).
[5] I. A. Abdelazim, A. A. Elezz, and M. Elsherbiny, Relation between single serum progesterone assay and viability of the first trimester pregnancy, Springer Plus, 1, no. 1, 1–5, (2012).
[6] J. Elson, R. Salim, A. Tailor, S. Banerjee, N. Zosmer, and D. Jurkovic, Prediction of early pregnancy viability in the absence of an ultrasonically detectable embryo, Ultrasound in Obstetrics and Gynecology, 21, no. 1, 57–61, (2003).
[7] J. Verhaegen, I. D. Gallos, N. M. Van Mello, M. Abdel-Aziz, Y. Takwoingi, H. Harb, J. J. Deeks, B. W. J. Mol, and A. Coomarasamy, Accuracy of single progesterone test to predict early pregnancy outcome in women with pain or bleeding: Meta-analysis of cohort studies, BMJ (Online), 345, no. 7879, Article ID e6077, (2012).
[8] L. Duan, D. Yan, W. Zeng, X. Yang, and Q. Wei, Predictive power progesterone combined with beta human chorionic gonadotropin measurements in the outcome of threatened miscarriage, Archives of Gynecology and Obstetrics, 283, no. 3, 431–435, (2011).
[9] N. Kadar, B. V. Caldwell, and R. Romero, A method of screening for ectopic pregnancy and its indications, Obstetrics and Gynecology, 58, no. 2, 162–166, (1981).
[10] Z. A. A. Al Jufairi, The value of serum progesterone measurement in early pregnancy, Bahrain Medical Bulletin, 22, no. 1, 18–20, (2000).
[11] MM. Al-Jeborry, Predictive Power of Serial Serum Beta Human Chorionic Gonadotropin Measurements in the Outcome of Pregnancy, Medical Journal of Babylon, p. 11, (2014).
[12] G. Konrad, First-trimester bleeding with falling HCG: Don’t assume miscarriage, Canadian Family Physician, 53, no. 5, 831–832, (2007).
[13] C. R. Gracia, M. D. Sammel, J. Chittams, A. C. Hummel, A. Shaunik, and K. T. Barnhart, Risk factors for spontaneous abortion in early symptomatic first-trimester pregnancies, Obstetrics and Gynecology, 106, no. 5 I, 993–999, (2005).
[14] E. De La Rochebrochard and P. Thonneau, Paternal age and maternal age are risk factors for miscarriage; Results of a multicentre European study, Human Reproduction, 17, no. 6, 1649–1656, (2002).
[15] J. Johns, S. Muttukrishna, M. Lygnos, N. Groome, and E. Jauniaux, Maternal serum hormone concentrations for prediction of adverse outcome in threatened miscarriage, Reproductive BioMedicine Online, 15, no. 4, article no. 2969, 413–421, (2007).
[16] S. Luisi, P. Florio, D. D’Antona, F. M. Severi, F. Sanseverino, S. Danero, and F. Petraglia, Maternal serum inhibin A levels are a marker of a viable trophoblast in incomplete and complete miscarriage, European Journal of Endocrinology, 148, no. 2, 233–236, (2003).
[17] G. C. Di Renzo, A. Mattei, M. Gojnic, and S. Gerli, Progesterone and pregnancy, Current Opinion in Obstetrics and Gynecology, 17, no. 6, 598–600, (2005).
[18] R. Mackenzie, M. Walker, A. Armson, and M. E. Hannah, Progesterone for the prevention of preterm birth among women at increased risk: A systematic review and meta-analysis of randomized controlled trials, American Journal of Obstetrics and Gynecology, 194, no. 5, 1234–1242, (2006).
[19] A. Sotiriadis, S. Papatheodorou, and G. Makrydimas, Threatened miscarriage: Evaluation and management, British Medical Journal, 329, no. 7458, 152–155, (2004).
[20] N. S. Qureshi, E. C. Edi-Osagie, V. Ogbo, S. Ray, and R. E. Hopkins, First trimester threatened miscarriage treatment with human chorionic gonadotrophins: A randomised controlled trial, BJOG: An International Journal of Obstetrics and Gynaecology, 112, no. 11, 1536–1541, (2005).
[21] A. García-Enguídanos, M. E. Calle, J. Valero, S. Luna, and V. Domínguez-Rojas, Risk factors in miscarriage: A review, European Journal of Obstetrics Gynecology and Reproductive Biology, 102, no. 2, 111–119, (2002).
[22] X. Weng, R. Odouli, and D.-K. Li, Maternal caffeine consumption during pregnancy and the risk of miscarriage: a prospective cohort study, American Journal of Obstetrics and Gynecology, 198, no. 3, 279–e1, (2008).