Risk Factors for Acute Myocardial Infarction in Young Adults: Literature Review


Myocardial infarction is the leading cause of death worldwide. Deaths from cardiovascular disease each year have increased due to higher levels of stressors, unhealthy lifestyles and others. In addition, according to the World Health Organization, there is usually one death from cardiovascular disease every two seconds, and a heart attack every five seconds. This research used a literature study design and assessed the quality of journals using a JBI cohort, cross-sectional, and case-control studies with the aim of obtaining quality journals in accordance with the research topic. 16 journals were obtained, consisting of six journals from Google Scholar, four journals from Science Direct, five journals from Pubmed, and one journal from Proquest. There are factors that influence myocardial infarction in young adults, namely comorbid factors, psychological factors, lifestyle factors, and gender factors. The comorbid factors that often occur are hypertension, diabetes, dyslipidemia, and obesity, while the genetic factors include a family history of myocardial infarction. Lifestyle factors consist of smoking, alcohol consumption, poor diet, and less activity. Men are more susceptible to myocardial infarction at a young age.

Keywords: factors, associated, myocardial infarction, young adults

[1] Mehran KR, Zena K. Infark miokard akut pada wanita muda : perspektif saat ini. 2018;267–284.

[2] Yusran H. Dukungan Keluarga Dan Intimasi Terhadap Persepsi Tingkat Nyeri Pada Pasien Infark Miokard Akut (IMA) [Internet]. CV IRDH. 2019 [cited 2022 Oct 28]. Available from: https://books.google.co.id/books?id=rZb7DwAAQBAJ&pg= PT3&source=gbs_toc_r&cad=3#v=onepage&q&f=false

[3] Wita IW. Cintailah Jantung Kita: Mencegah Serangan Jantung. Bhuvana Saraswati Foundation; 2016.

[4] Faulata RA, Laksono AD, Wulandari RD. Heart Disease in Indonesia in 2018: An Ecological Analysis. Indian J Forensic Med Toxicol. 2021;15(3):3927–33.

[5] Muflihah U, Chinnawong T, Kritpracha C. Complementary therapies used by Indonesians with myocardial infarction [Internet]. Holist Nurs Pract. 2021 Jan-Feb;35(1):19– 28. [cited 2022 Oct 28] Available from: https://journals.lww.com/hnpjournal/Fulltext/ 2021/01000/Complementary_Therapies_Used_by_Indonesians_With.4.aspx

[6] Yang J, Biery DW, Singh A, Divakaran S, DeFilippis EM, Wu WY, et al. Risk Factors and Outcomes of Very Young Adults Who Experience Myocardial Infarction: The Partners YOUNG-MI Registry [Internet]. Am J Med. 2020 May;133(5):605–612.e1. [cited 2022 Oct 28] Available from: http://www.amjmed.com/article/S0002934319309623/ fulltext

[7] Gupta MD, Gupta P, Mp G, Roy A, Qamar A. Risk factors for myocardial infarction in very young South Asians [Internet]. Curr Opin Endocrinol Diabetes Obes. 2020 Apr;27(2):87–94. [cited 2022 Oct 28] Available from: https://journals.lww.com/co-endocrinology/Fulltext/2020/ 04000/Risk_factors_for_myocardial_infarction_in_very.2.aspx

[8] Krittanawong C, Liu Y, Mahtta D, Narasimhan B, Wang Z, Jneid H, et al. Non-traditional risk factors and the risk of myocardial infarction in the young in the US populationbased cohort. Int J Cardiol Heart Vasc. 2020 Sep;30:100634.

[9] Zasada W, Bobrowska B, Plens K, Dziewierz A, Siudak Z, Surdacki A, et al. Acute myocardial infarction in young patients [Polish Hear Journal]. Kardiol Pol. 2021;79(10):1093–8. [cited 2022 Oct 28] Available from: https://journals.viamedica. pl/kardiologia_polska/article/view/KP.a2021.0099/64772

[10] Gulati R, Behfar A, Narula J, Kanwar A, Lerman A, Cooper L, et al. Acute Myocardial Infarction in Young Individuals [Internet]. Mayo Clin Proc. 2020 Jan;95(1):136–56. [cited 2022 Oct 28] Available from: http://www.mayoclinicproceedings.org/article/ S0025619619304215/fulltext

[11] Sinha SK, Krishna V, Thakur R, Kumar A, Mishra V, Jha MJ, et al. Acute myocardial infarction in very young adults: A clinical presentation, risk factors, hospital outcome index, and their angiographic characteristics in North India-AMIYA Study. ARYA Atheroscler [Internet]. 2017 [cited 2022 Oct 28];13(2):79. Available from: /pmc/articles/PMC5628855/

[12] Devi GA, Aryabiantara IW, Hartawan IU. Profil Penggunaan Antikoagulan Pada Pasien Kardiovaskular yang Dirawat di Ruang ICCU RSUP Sanglah Periode Januari 2016 - Juni 2016. E-jurnal Med [Internet]. 2018 [cited 2022 Oct 28];7(10). Available from: https://ojs.unud.ac.id/index.php/eum/article/view/42756/25965

[13] Ningsih. Perceraian Usia Muda Perspektif Sosiologi Hukum. Guepedia; 2020.

[14] Venkateshwarlu N, Gandaiah P, Indira G, Reddy PA, Sivarajappa P. Acute Myocardial Infarction in Young Below 30 Years of Age; Special Insight to Risk Factors. Int J Med Appl Sci. 2013;2(4):90–100.

[15] Bhardwaj R, Kandoria A, Sharma R. Myocardial infarction in young adults-risk factors and pattern of coronary artery involvement. Niger Med J. 2014 Jan;55(1):44–7.