Activity of Hair Tonic Nanoemulsion with Candlenut Oil (Aleurites Moluccana) on Mice (Mus Musculus)
Abstract
Hair loss is one of the most common hair problems, which usually happens at about 100 strands every day. It has been shown that candlenut oil can help to overcome the problem of hair loss. This study aimed to determine the effect of a hair tonic nanoemulsion in varying concentrations of candlenut oil on accelerating hair growth in Mus musculus. A nanoemulsion hair tonic was created because doing so can increase the solubilization of the oil. In the nanoemulsion form, the penetration of the medicinal ingredients into the skin is accelerated. In this study, nanoemulsions were produced with 5%, 6%, and 7% candlenut oil as formula 1, formula 2, and formula 3. A base without candlenut oil was used as a negative control, and a ginseng hair tonic obtained from the market was used as a positive control. The researchers conducted the hair tonic test by measuring the hair growth and hair density of the Mus musculus at 21 days. The hair growth was -0.442 mm for the negative control; 2.255 mm for the positive control; 1.352 mm for formula 1; 1.773 mm for formula 2; and 3.649 mm for formula 3. The hair weight was 3.20 mg for the negative control; 2.22 mg for the positive control; 2.26 mg for formula 1; 4.54 mg for formula 2; and 6.70 mg for formula 3. This study therefore demonstrated that hair tonic nanoemulsion of candlenut oil can accelerate hair growth.
Keywords: candlenut oil, hair growth, hair tonic nanoemulsion
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