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Amalia, S. D., Fitriana Putri, N. Y., & Anggraeni, A. D. (2022). The Potential of Phyllanthus Niruri Plant Secondary Metabolites in Providing Antiviral Protection Against Sars-Cov-2: A Literature Review. KnE Medicine, 2(3), 614–620. https://doi.org/10.18502/kme.v2i3.11915

https://doi.org/10.18502/kme.v2i3.11915

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authors

  • Septia Devi Amalia

    Septia Devi Amalia

    Pharmacy Department, Health Science Faculty, University of Muhammadiyah Malang, Indonesia
  • Nia Yuniar Fitriana Putri

    Nia Yuniar Fitriana Putri

    Pharmacy Department, Health Science Faculty, University of Muhammadiyah Malang, Indonesia
  • Amaliyah Dina Anggraeni

    Amaliyah Dina Anggraeni

    Pharmacy Department, Health Science Faculty, University of Muhammadiyah Malang, Indonesia

Published Date

  • Sep 15, 2022

The Potential of Phyllanthus Niruri Plant Secondary Metabolites in Providing Antiviral Protection Against Sars-Cov-2: A Literature Review

KnE Medicine / The International Conference of Medicine and Health (ICMEDH) / Pages 614–620

Abstract

Covid-19 is a disease that causes respiratory tract infections in humans. The Covid-19 pandemic has spread throughout the world. Meniran (Phyllanthus niruri) is a plant that has been empirically shown to be an antiviral. This study aimed to determine the potential of Phyllanthus niruri and its compounds as an antiviral for SARS-CoV-2 through a literature review. The data were analyzed descriptively using the NVIVO 12 Plus software. The parameters used were the hierarchy chart, cluster analysis, and world cloud. The results showed that two secondary metabolites of Phyllanthus niruri have the potential to provide antiviral protection against SARS-CoV-2, namely quercetin and rutin. Further research is needed to examine the validity of these findings through triangulation of the scientific reports and research in the laboratory.


Keywords: antivirus, Phyllanthus niruri, SARS-CoV-2

References
[1] A.N.T. Adjeng, R. Ruslin, L.O.M. Fitrawan, and A. Pascayantri, “Sosialisasi dan Edukasi Pemanfaatan Tanaman Berkhasiat Obat Dalam Menghadapi Masa Pandemi COVID19 di Kota Kendari.,” Jurnal Mandala Pengabdian Masyarakat. vol. 1, no. 2, pp. 62–69, 2020.


[2] Badan POM, Buku Saku Obat Tradisional Untuk Memelihara Daya Tahan Tubuh. Badan POM, Jakarta, 2020.


[3] B. Pan, S. Fang, J. Zhang, et al., “Chinese herbal compounds against SARS-CoV2: Puerarin and quercetin impair the binding of viral S-protein to ACE2 receptor.,” Computational and Structural Biotechnology Journal. vol. 18, pp. 3518–3527, 2020.


[4] P.K. Agrawal, C. Agrawal, and G. Blunden, “Rutin: A Potential Antiviral for Repurposing as a SARS-CoV-2 Main Protease (Mpro) Inhibitor:,” SAGE Journals. vol. 16, no. 4, pp. 1–12, 2021.