ANTICANCER AND ANTIAGGREGATION OF SEAWEED EXTRACT

Abstract

Exploration of seaweed potential as sources of bioactive compounts were studied and found two type seaweeds from in Bali such as Caulerpa rasemosa and Gracillaria sp had potential as food suplements and prepared and consumed as food. These seaweeds were used as vegetables in daily diet as side dishes or can be consumed alone. Their bioactive components of these seaweeds were explored for degenerative diseases. Gracillaria sp or bukung hijau were extracted with different solvents and tested qualitatively for possible bioactive component. as anti cancer agents and anti platelet aggregations were performed in vitro. Using cancer cell of mice (C3H) and New Zealang Rabbits Platelet. The results showed that anti cancer growth of the extract was 7th fraction of the extract with 78% activities and LD50 was 0.1 ppm. The anti platelets aggregation optimum of the extract was 13.2%. The formulation of food supplement from these seaweed may benefit to produce functional food related to health.

Keywords: seaweed extract, anti-cancer, anti platelet aggregation

 

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