Complementary therapies in both music and murottal therapy are beleaved effective because the songs and Quranic verses can have a therapeutic effect through the mind and physiology of human. This study was to identify differences inﬂuence of murotal therapy and music therapy in lowering blood pressure, This study used a quasi-experimental with a pretest-posttest approach design. The sample used in this study were 30 respondents who are divided into 2 intervention groups, group 1used murottal and group 2 terpy murottal used music therapy in hypertensive patients in Kepuh village of used Rw 04 and 05 Palimanan Cirebon sampling technique cluster rondom sampling. Statistical tests using t test. Results of data analysis showed there is signiﬁcantdifferencebetweenthebloodpressureaftermurottaltherapywiththeblood pressure after music therapy in hypertensive patients, whith p value 0,001. Age and genderfactorsareconsideredhaveinﬂuenceinloweringbloodpressureaftermurottal therapy. The results of this study are expected to be the basis of complementary therapies and can be implemented as independent and innovative interventions in the nursing care of patients with hypertension.