Glomerulus Filtration Rate (GFR) Estimation Value Using Cockcroft and Gault Equation Against Community Exposure to Mercury at Artisanal and Small Scale Gold Mining (ASGM) Area in Lebaksitu Village, District of Lebak, Banten

Abstract

The usage of mercury in Artisanal and Small Scale Gold Mining (ASGM) is quite troublesome because, within the process, ASGM produces mercury within its waste to the environment that might become pollution. Exposure of mercury to the body in long period could threaten the body’s health such as kidney as excretion organ that
exerts toxic materials from the body. Glomerulus filtration rate (GFR) is one parameter to evaluate the work of the kidney and the stadium of the kidney disease. This research aimed to understand the relation between mercury level in hair and GFR and used cross-sectional design with measured variables including mercury level in hair, respondent characteristic, and GFR. The respondents included 58 people. The output showed that 51.7% of respondents had mercury level above the guideline (> 2 ppm) in their hair and 43.1% of respondents had experienced a decrease in GFR (abnormality in kidney function). The decrease in GFR was caused by age and mercury level in hair. This decrease can be prevented by consuming more water, reducing medicine consumption, and conducting promotion about health service and the impact of mercury on public health.



Keywords: glomerulus filtration rate (GFR), mercury level in hair, Artisanal and Small
Scale Gold Mining (ASGM)

References
[1] Guyton AC, Hall JE. Buku Ajar Fisiologi Kedokteran (Terjemahan). 9th ed. Setiawan I, editor. Jakarta: EGC; 1997


[2] Soemirat. (2009). Toksikologi Lingkungan. Gajah Mada University Press. Yogyakarta.


[3] O’Callaghan C. At a Glance Sistem Ginjal (Terjemahan). 2nd ed. Safitri A, Astikawati R, editors. Jakarta: Penerbit Erlangga; 2009.


[4] Agung L.,N. Hutamadi. Raharjo (2012)., Paparan Merkuri Di Daerah Pertambangan Emas Rakyat Cisoka, Kabupaten Lebak, Provinsi Banten: Suatu Tinjauan Geologi Medis. Makalah Ilmiah. Buletin Sumber Daya
Geologi Volume 7 No 3.


[5] Lubis, Ira P (2016). Analisis Kejadian Stres Oksidatif Melalui Pengukuran Malondialdehide (MDA) pada Masyarakat Terpajan Merkuri di Pertambangan Emas Skala Kecil (PESK) Desa Lebaksitu, Kabupaten Lebak, Banten. Tesis. Depok. FKM Universitas Indonesia


[6] US EPA. (2006). Enviroment Protection Agency, Mercury, Human Health.


[7] Bangun, Herianto. 2014. Pengaruh Kadar Merkuri(Hg) Dalam Urin Terhadap Fungsi Ginjal Pada Penambang Emastradisional Di Desa Panton Luas Kecamatan Sawang Kabupaten Aceh Selatan. Tesis. Medan. FK USU.


[8] Smeltzer & Bare. 2002. Buku Ajar Keperawatan Medikal Bedah. Jakarta: EGC.


[9] Wilson, L.M and Price, S.A. 2006. Patofi siologi Konsep Klinis Proses-Proses Penyakit. Volume 2 Edisi 6. Jakarta.


[10] Weinstein J.R., Anderson S., 2010. The Aging Kidney: Physiological Changes. Advances in Chronic Kidney.


[11] Ginting, Flora, 2008. Karakteristik Penderita Gagal Ginjal Kronik (GGK) Yang Di Rawat Inap Di RSUP H Adam Malik Medan Tahun 2007. Skripsi. Fakultas Kesehatan Masyarakat USU, Medan


[12] Warsono, S (2002) Pengaruh Bahan Tambal Amalgam Terhadap Kadar Merkuri pada Darah, Urin, Tinja dan Rambut Kepala Jurnal Kedokteran Gigi UI Vol 7 No.1 : 23-30


[13] Inswiasri dan Kusnoputranto. Pajanan Hg Pada Petambang Emas Tradisional Di Kabupaten Gunung Mas, Kalimantan Tengah. Jurnal Ekologi Kesehatan. Vol. 10 No.2. Juni 2011 : 72-82.


[14] Hidayati,dkk (2008), Hubungan antara hipetensi, merokok dam minuman suplemen. Berita Kedokteran Masyarakat, Vol. 24,No.4


[15] Kumala, B. 2016. Hati-hati Salah Konsumsi Obat Analgesik Beresiko Gagal Ginjal. http: //nationalgeographic.co.id/berita/2016/02/.


[16] Ana. 2015. 14 Penyebab Gagal Ginjal Akut dan Kronik.http://halosehat.com/penyakit/penyakit-ginjal/ penyebab-gagal-ginjal.