Bacterial Carriage of Pathogenic Antibiotic-resistant Staphylococci Among Conditionally Healthy Infants and Preschool-age Children

Abstract

Staphylococci are related to opportunistic microorganisms and are part of normal human microflora. However, there are varieties that can cause pyoinflammatory diseases in organisms with weakened immune status. In the event of an inadequate therapeutic approach, they are preserved in the body, and the person becomes a bacterial carrier and a source of dissemination of pathogenic microorganisms. The formation of antibiotic resistance also plays a significant role in the emergence of bacterial carriage. The situation is especially serious in organized children’s groups, where children are in close contact with one another. Thus, the study of the prevalence rate of antibiotic resistance among pathogenic strains of staphylococci in children’s groups is topical and worthy of attention. The purpose of this work is to identify carriers of pathogenic and antibiotic resistant staphylococci isolated from the microflora of the oral cavity of preschool children considered healthy. The results of the research can prove useful in practical healthcare and, particularly, in pediatric practice.


Keywords: staphylococci, pathogenic cocci, bacterial carriage, antibiotic resistance, infant morbidity rate

References
[1] V.M. Chervinets, O.A. Gavrilova, and Yu.V. Chervinets, “Oral microflora of children aged 7–11 years,” Successes of Modern Natural Science, no. 2, pp. 73–74, 2009.


[2] G. A. Sansygina, and G. S. Koval, “Recurrent respiratory infection children: Problems of diagnosis, pathogenesis and therapy,” Lechashchiy Vrach, no. 1, 2009 URL: https://www.lvrach.ru/2009/01/5897153/ (Reference date: 15.04.17).


[3] A.Yu. Deryusheva, and A.V. Deryusheva, “Composition of the microflora of the upper respiratory tract in RRI children. Prospects for modern medicine development,” iss. 3, in Proceedings of the International Scientific and Practical Conference, Voronezh, 2016, 224 p., ITSRON, 2017.


[4] Yu.O. Khlynina, “Characterization of microbial biocenoses of mucous membranes in RRI children: Cand. Sci. (Medicine) thesis. Volgograd, 2012.


[5] V.N. Turchina, L.A. Dulkin, and N.A. Tempel, “Antibiotic therapy in the treatment of respiratory infections in children at the outpatient stage,” Pediatric Pharmacology, no. 3, pp. 66–69, 2014.


[6] Yu. Rusetsky, T. Sedykh, and V. Smirnova, “Antibiotic susceptibility of nasopharyngeal microflora in children with adenoids,” Vrach, no. 13, pp. 34–37, 2011 (in Russian)


[7] P. G. Bedin, S.A. Lyalikov, and T.V. Nekrashevich, “Antibiotic susceptibility of Staphylococcus aureus in children of the Grodno region suffering from chronic tonsillitis,” Problems of health and ecology, no. 3, pp. 87–91, 2014.


[8] Order of the Ministry of Health of the USSR, 22.04.1985, no. 535 “On the unification of microbiological (bacteriological) research methods used in clinical diagnostic laboratories of medical and preventive institutions,” 126 p., Moscow, 1989.


[9] A.S. Labinskaya, “Microbiology with the technique of microbiological research: Textbook,” 394 p., Moscow, Meditsina, 1978.


[10] Evaluation of Microorganisms Sensitivity to Antibacterial Medications: Methodological Guidelines MUK 4.2.1890-04. Approved and put into effect by the Chief State Sanitary Doctor of the Russian Federation G.G. Onishchenko, 04.03.2004.