Editorial – Corneal Cross-linking for Keratoconus: Exploring the Issues Regarding Accelerated Protocols and Thin Corneas

Abstract

This is an Editorial and does not have an abstract. Please download the PDF or view the article HTML.

Keywords:

NA

References
Sufi ARS, Gohil MN, Keenan JD, Prajna NV. Structural changes in thin keratoconic corneas following crosslinking with hypotonic riboflavin: findings on in vivo confocal microscopy. J Ophthalmic Vis Res 2021;16:325–337.

2. Salman AMDTR, Haddad YH, Shabaan RH, Askar MZ. Accelerated versus standard corneal cross-linking for progressive keratoconus in Syria. J Ophthalmic Vis Res 2021;16:338–348.

3. Randleman JB, Khandelwal SS, Hafezi F. Corneal crosslinking. Surv Ophthalmol 2015;60:509–523.

4. Wollensak G, Sporl E, Seiler T. [Treatment of keratoconus by collagen cross linking]. Ophthalmologe 2003;100:44– 49.

5. Kling S, Richoz O, Hammer A, Tabibian D, Jacob S, Agarwal A, et al. Increased biomechanical efficacy of corneal crosslinking in thin corneas due to higher oxygen availability. J Refract Surg 2015;31:840–846.

6. Richoz O, Hammer A, Tabibian D, Gatzioufas Z, Hafezi F. The biomechanical effect of corneal collagen cross-linking (CXL) with riboflavin and UV-A is oxygen dependent. Transl Vis Sci Technol 2013;2:6.

7. Torres-Netto EA, Kling S, Hafezi N, Vinciguerra P, Randleman JB, Hafezi F. Oxygen diffusion may limit the biomechanical effectiveness of iontophoresis-assisted transepithelial corneal cross-linking. J Refract Surg 2018;34:768–774.

8. Hammer A, Richoz O, Arba Mosquera S, Tabibian D, Hoogewoud F, Hafezi F. Corneal biomechanical properties at different corneal cross-linking (CXL) irradiances. Invest Ophthalmol Vis Sci 2014;55:2881–2884.

9. Deshmukh R, Hafezi F, Kymionis GD, Kling S, Shah R, Padmanabhan P, et al. Current concepts in crosslinking thin corneas. Indian J Ophthalmol 2019;67:8–15.

10. Hafezi F, Mrochen M, Iseli HP, Seiler T. Collagen crosslinking with ultraviolet-A and hypoosmolar riboflavin solution in thin corneas. J Cataract Refract Surg 2009;35:621–624.

11. Jacob S, Kumar DA, Agarwal A, Basu S, Sinha P, Agarwal A. Contact lens-assisted collagen cross-linking (CACXL): a new technique for cross-linking thin corneas. J Refract Surg 2014;30:366–372.

12. Hafezi F, Kling S, Gilardoni F, Hafezi N, Hillen M, Abrishamchi R, et al. Individualized corneal cross-linking with riboflavin and UV-A in ultrathin corneas: the Sub400 protocol. Am J Ophthalmol 2021;224:133–142.