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Bagheri M, Ahoor M-H, Jafari A, Sadat Hashemi H, Mohammadkhani M. Pattern of Uveitis in Iran: A Systematic Review. JOVR [Internet]. 2021Jan.20 [cited 2024May5];16(1):93–102. Available from: https://knepublishing.com/index.php/JOVR/article/view/8255
https://doi.org/10.18502/jovr.v16i1.8255
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- Cited by 3 articles
authors
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Masood Bagheri
Masood Bagheri
Department of Ophthalmology, Imam Khomeini Eye Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
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Mohammad-Hosein Ahoor
Mohammad-Hosein Ahoor
Department of Ophthalmology, Nikookari Eye Center, Tabriz University of Medical Sciences, Tabriz, Iran
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Ahad Jafari
Ahad Jafari
Department of Ophthalmology, Nikookari Eye Center, Tabriz University of Medical Sciences, Tabriz, Iran
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Hesam Sadat Hashemi
Hesam Sadat Hashemi
Department of Ophthalmology, Nikookari Eye Center, Tabriz University of Medical Sciences, Tabriz, Iran
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Mehdi Mohammadkhani
Mehdi Mohammadkhani
Department of Ophthalmology, Nikookari Eye Center, Tabriz University of Medical Sciences, Tabriz, Iran
Published Date
- Jan 20, 2021
Pattern of Uveitis in Iran: A Systematic Review
Abstract
Purpose: Uveitis is the third leading cause of blindness worldwide. This study aimed to summarize the pattern of uveitis in Iran through a systematic review.
Methods: This review was conducted according to the guidelines for systematic reviews in the following four steps: literature search, study selection and assessment, inclusion and exclusion criteria, and statistical analysis.
Results: One hundred and fifteen articles were identified by an encyclopedic literature search, and three independent investigators examined them according to the defined inclusion and exclusion criteria. Eventually, 109 manuscripts were retrieved and six cross-sectional studies covering 3,567 patients were included and reviewed. According to the results, the mean age of patients was 40 years, and sex was not a statistically significant predisposing factor. The most common anatomical pattern of involvement was anterior uveitis, and the prevalence of the other three types of uveitis, including middle, posterior, and pan-uveitis, were almost equal. Overall, the most common etiologies of uveitis in the Iranian population were idiopathic uveitis, toxoplasmosis, Behcet’s syndrome, and Fuchs heterochromic iridocyclitis.
Conclusion: This study depicted the pattern of uveitis in Iranian society; this can help physicians in the diagnostic approach, management, and treatment of patients.
Keywords:
Epidemiology, Iran, Systematic Review, Uveitis
References
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10. Oruc S, Kaplan AD, Galen M, Kaplan HJ. Uveitis referral pattern in a midwest university eye center. Ocul Immunol Inflamm 2003;11:287–298.
11. Cunningham ET, Suhler EB. Childhood uveitis—young patients, old problems, new perspectives. J AAPOS 2008;12:537–538.
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13. Zein G, Berta A, Foster S. Multiple sclerosis-associated uveitis. Ocul Immunol Inflamm 2004;12:137–142.
14. Yang P, Zhang Z, Zhou H, Li B, Huang X, Gao Y, et al. Clinical patterns and characteristics of uveitis in a tertiary center for uveitis in China. Curr Eye Res 2005;30:943– 948.
15. Khairallah M, Yahia SB, Ladjimi A, Messaoud R, Zaouali S, Attia S, et al. Pattern of uveitis in a referral centre in Tunisia, North Africa. Eye 2007;21:33.
16. Hamade IH, Elkum N, Tabbara KF. Causes of uveitis at a referral center in Saudi Arabia. Ocul Immunol Inflamm 2009;17:11–16.
17. De-la-Torre A, López-Castillo CA, Rueda JC, Mantilla RD, Gómez-Marín JE, Anaya JM. Clinical patterns of uveitis in two ophthalmology centres in Bogota, Colombia. Clin Eexp Ophthalmol 2009;37:458–466.
18. Wakabayashi T, Morimura Y, Miyamoto Y, Okada AA. Changing patterns of intraocular inflammatory disease in Japan. Ocul Immunol Inflamm 2003;11:277–286.
19. Tugal-Tutkun I. Behçet disease in the developing world. Int Ophthalmol Clin 2010;50:87–98.
20. Bloch-Michel E, Nussenblatt RB. International Uveitis Study Group recommendations for the evaluation of intraocular inflammatory disease. Am J Ophthalmol 1987;103:234–235.
21. Group SoUNW. Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. Am J Ophthalmol 2005;140:509–516.
22. Rathinam S, Namperumalsamy P. Global variation and pattern changes in epidemiology of uveitis. Indian J Ophthalmol 2007;55:173.
23. Egger M, Dickersin K, Smith GD. Problems and limitations in conducting systematic reviews. In: Systematic reviews in health care: meta-analysis in context; 2001:43–68.
24. Moons KG, de Groot JA, Bouwmeester W, Vergouwe Y, Mallett S, Altman DG, et al. Critical appraisal and data extraction for systematic reviews of prediction modelling studies: the CHARMS checklist. PLoS Med 2014;11:e1001744.
25. Hosseini SM, Shoeibi N, Ebrahimi R, Ghasemi M. Patterns of uveitis at a tertiary referral center in northeastern Iran. J Ophthalmic Vis Res 2018;13:138–143.
26. Ghavidel LA, Mousavi F, Bagheri M, Asghari S. Clinical course of uveitis in children in a tertiary ophthalmology center in northwest Iran. Crescent J Medical Biol Sci 2017;4:200–204.
27. Rahimi M, Oustad M, Ashrafi A. Demographic and clinical features of pediatric uveitis at a tertiary referral center in Iran. Middle East Afr J Ophthalmol 2016;23:237–240.
28. Kianersi F, Mohammadi Z, Ghanbari H, Ghoreyshi SM, Karimzadeh H, Soheilian M. Clinical patterns of uveitis in an Iranian tertiary eye-care center. Ocul Immunol Inflamm 2015;23:278–282.
29. Rahimi M, Mirmansouri G. Patterns of uveitis at a tertiary referral center in southern Iran. J Ophthal Vis Res 2014;9:54.
30. Soheilian M, Heidari K, Yazdani S, Shahsavari M, Ahmadieh H, Dehghan M. Patterns of uveitis in a tertiary eye care center in Iran. Ocul Immunol Inflamm 2004;12:297–310.
31. Borenstein M, Hedges LV, Higgins JP, Rothstein HR. A basic introduction to fixed-effect and random-effects models for meta-analysis. Res Synth Methods 2010;1:97–111.
32. Soheylian M, Heydari K, Khosravi-Jafari M. Epidemiology and referral pattern of uveitis in a tertiary eye care center in Tehran; 2002.
33. Kianersi F. Clinical patterns of uveitis in an Iranian tertiary eye care center. Bina J Ophthalmol 2005;10:147–154.
34. Ghavidel LA, Arshadi M, Mousavi F. Clinical patterns and causes of posterior uveitis in a tertiary referral eye center in northwest of Iran. Crescent J Medical Biol Sci 2018;5:345–349.
35. Das D, Bhattacharjee H, Bhattacharyya PK, Jain L, Panicker M, Das K, et al. Pattern of uveitis in North East India: a tertiary eye care center study. Indian J Ophthalmol 2009;57:144.
36. Pathanapitoon K, Kunavisarut P, Ausayakhun S, Sirirungsi W, Rothova A. Uveitis in a tertiary ophthalmology centre in Thailand. Br J Ophthalmol 2008;92:474–478.
37. Henderly DE, Genstler AJ, Smith RE, Rao NA. Changing patterns of uveitis. Am J Ophthalmol 1987;103:131–136.
38. Chams H, Rostami M, Mohammadi S, Ohno S. Epidemiology and prevalence of uveitis: review of literature. Iran J Ophthalmol 2009;21:4–16.
39. Khairallah M, Gargouri S. Epidemiology of uveitis in the Middle East and North Africa. Acta Ophthalmologica 2010;88.
40. Nashtaei EM, Soheilian M, Herbort CP, Yaseri M. Patterns of uveitis in the Middle East and Europe. J Ophthal Vis Res 2011;6:233.
2. de Smet MD, Taylor SR, Bodaghi B, Miserocchi E, Murray PI, Pleyer U, et al. Understanding uveitis: the impact of research on visual outcomes. Prog Retin Eye Res 2011;30:452–470.
3. McCannel CA, Holland GN, Helm CJ, Cornell PJ, Winston JV, Rimmer TG, et al. Causes of uveitis in the general practice of ophthalmology. Am J Ophthalmol 1996;121:35– 46.
4. London NJ, Rathinam SR, Cunningham ET. The epidemiology of uveitis in developing countries. Int Ophthalmol Clin 2010;50:1–17.
5. Vallet H, Seve P, Biard L, Baptiste Fraison J, Bielefeld P, Perard L, et al. Infliximab versus adalimumab in the treatment of refractory inflammatory uveitis: a multicenter study from the French Uveitis Network. Arthritis Rheumatol 2016;68:1522–1530.
6. Tsirouki T, Dastiridou A, Symeonidis C, Tounakaki O, Brazitikou I, Kalogeropoulos C, et al. A focus on the epidemiology of uveitis. Ocul Immunol Inflamm 2018;26:2–16.
7. Jaffe GJ, Dick AD, Brézin AP, Nguyen QD, Thorne JE, Kestelyn P, et al. Adalimumab in patients with active noninfectious uveitis. New Engl J Med 2016;375:932–943.
8. Daniel E, Pistilli M, Pujari SS, Kaçmaz RO, Nussenblatt RB, Rosenbaum JT, et al. Risk of hypotony in noninfectious uveitis. Ophthalmology 2012;119:2377–2385.
9. Chang JH-M, Wakefield D. Uveitis: a global perspective. Ocul Immunol Inflamm 2002;10:263–279.
10. Oruc S, Kaplan AD, Galen M, Kaplan HJ. Uveitis referral pattern in a midwest university eye center. Ocul Immunol Inflamm 2003;11:287–298.
11. Cunningham ET, Suhler EB. Childhood uveitis—young patients, old problems, new perspectives. J AAPOS 2008;12:537–538.
12. Laroni A, Calabrese M, Perini P, Albergoni MP, Ranzato F, Tiberio M, et al. Multiple sclerosis and autoimmune diseases. J Neurol 2006;253:636–639.
13. Zein G, Berta A, Foster S. Multiple sclerosis-associated uveitis. Ocul Immunol Inflamm 2004;12:137–142.
14. Yang P, Zhang Z, Zhou H, Li B, Huang X, Gao Y, et al. Clinical patterns and characteristics of uveitis in a tertiary center for uveitis in China. Curr Eye Res 2005;30:943– 948.
15. Khairallah M, Yahia SB, Ladjimi A, Messaoud R, Zaouali S, Attia S, et al. Pattern of uveitis in a referral centre in Tunisia, North Africa. Eye 2007;21:33.
16. Hamade IH, Elkum N, Tabbara KF. Causes of uveitis at a referral center in Saudi Arabia. Ocul Immunol Inflamm 2009;17:11–16.
17. De-la-Torre A, López-Castillo CA, Rueda JC, Mantilla RD, Gómez-Marín JE, Anaya JM. Clinical patterns of uveitis in two ophthalmology centres in Bogota, Colombia. Clin Eexp Ophthalmol 2009;37:458–466.
18. Wakabayashi T, Morimura Y, Miyamoto Y, Okada AA. Changing patterns of intraocular inflammatory disease in Japan. Ocul Immunol Inflamm 2003;11:277–286.
19. Tugal-Tutkun I. Behçet disease in the developing world. Int Ophthalmol Clin 2010;50:87–98.
20. Bloch-Michel E, Nussenblatt RB. International Uveitis Study Group recommendations for the evaluation of intraocular inflammatory disease. Am J Ophthalmol 1987;103:234–235.
21. Group SoUNW. Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. Am J Ophthalmol 2005;140:509–516.
22. Rathinam S, Namperumalsamy P. Global variation and pattern changes in epidemiology of uveitis. Indian J Ophthalmol 2007;55:173.
23. Egger M, Dickersin K, Smith GD. Problems and limitations in conducting systematic reviews. In: Systematic reviews in health care: meta-analysis in context; 2001:43–68.
24. Moons KG, de Groot JA, Bouwmeester W, Vergouwe Y, Mallett S, Altman DG, et al. Critical appraisal and data extraction for systematic reviews of prediction modelling studies: the CHARMS checklist. PLoS Med 2014;11:e1001744.
25. Hosseini SM, Shoeibi N, Ebrahimi R, Ghasemi M. Patterns of uveitis at a tertiary referral center in northeastern Iran. J Ophthalmic Vis Res 2018;13:138–143.
26. Ghavidel LA, Mousavi F, Bagheri M, Asghari S. Clinical course of uveitis in children in a tertiary ophthalmology center in northwest Iran. Crescent J Medical Biol Sci 2017;4:200–204.
27. Rahimi M, Oustad M, Ashrafi A. Demographic and clinical features of pediatric uveitis at a tertiary referral center in Iran. Middle East Afr J Ophthalmol 2016;23:237–240.
28. Kianersi F, Mohammadi Z, Ghanbari H, Ghoreyshi SM, Karimzadeh H, Soheilian M. Clinical patterns of uveitis in an Iranian tertiary eye-care center. Ocul Immunol Inflamm 2015;23:278–282.
29. Rahimi M, Mirmansouri G. Patterns of uveitis at a tertiary referral center in southern Iran. J Ophthal Vis Res 2014;9:54.
30. Soheilian M, Heidari K, Yazdani S, Shahsavari M, Ahmadieh H, Dehghan M. Patterns of uveitis in a tertiary eye care center in Iran. Ocul Immunol Inflamm 2004;12:297–310.
31. Borenstein M, Hedges LV, Higgins JP, Rothstein HR. A basic introduction to fixed-effect and random-effects models for meta-analysis. Res Synth Methods 2010;1:97–111.
32. Soheylian M, Heydari K, Khosravi-Jafari M. Epidemiology and referral pattern of uveitis in a tertiary eye care center in Tehran; 2002.
33. Kianersi F. Clinical patterns of uveitis in an Iranian tertiary eye care center. Bina J Ophthalmol 2005;10:147–154.
34. Ghavidel LA, Arshadi M, Mousavi F. Clinical patterns and causes of posterior uveitis in a tertiary referral eye center in northwest of Iran. Crescent J Medical Biol Sci 2018;5:345–349.
35. Das D, Bhattacharjee H, Bhattacharyya PK, Jain L, Panicker M, Das K, et al. Pattern of uveitis in North East India: a tertiary eye care center study. Indian J Ophthalmol 2009;57:144.
36. Pathanapitoon K, Kunavisarut P, Ausayakhun S, Sirirungsi W, Rothova A. Uveitis in a tertiary ophthalmology centre in Thailand. Br J Ophthalmol 2008;92:474–478.
37. Henderly DE, Genstler AJ, Smith RE, Rao NA. Changing patterns of uveitis. Am J Ophthalmol 1987;103:131–136.
38. Chams H, Rostami M, Mohammadi S, Ohno S. Epidemiology and prevalence of uveitis: review of literature. Iran J Ophthalmol 2009;21:4–16.
39. Khairallah M, Gargouri S. Epidemiology of uveitis in the Middle East and North Africa. Acta Ophthalmologica 2010;88.
40. Nashtaei EM, Soheilian M, Herbort CP, Yaseri M. Patterns of uveitis in the Middle East and Europe. J Ophthal Vis Res 2011;6:233.