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Mohammadpour M, Masoumi A, Dehghan M, Hashemian MN, Karami SA, Mahmoudi A. MyoRing Implantation with and without Corneal Collagen Crosslinking for the Management of Keratoconus. JOVR [Internet]. 2020Oct.25 [cited 2024Apr.23];15(4):486–492. Available from: https://knepublishing.com/index.php/JOVR/article/view/7790

https://doi.org/10.18502/jovr.v15i4.7790

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authors

  • Mehrdad Mohammadpour

    Mehrdad Mohammadpour

    Translational Ophthalmology Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
  • Ahmad Masoumi

    Ahmad Masoumi

    Translational Ophthalmology Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
  • Mahmoud Dehghan

    Mahmoud Dehghan

    Translational Ophthalmology Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
  • Mohammad Nasser Hashemian

    Mohammad Nasser Hashemian

    Translational Ophthalmology Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
  • Shahab Addin Karami

    Shahab Addin Karami

    Translational Ophthalmology Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
  • Alireza Mahmoudi

    Alireza Mahmoudi

    Translational Ophthalmology Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran

Published Date

  • Oct 25, 2020
This journal is publishing all the articles under Creative Commons Attribution License CC BY 4.0.

MyoRing Implantation with and without Corneal Collagen Crosslinking for the Management of Keratoconus

Journal of Ophthalmic and Vision Research (JOVR) / October–December 2020, Volume 15, Issue 4 / Pages 486–492

Abstract

Purpose: To evaluate the safety and efficacy of femtosecond laser-assisted MyoRing implantation with concurrent corneal collagen crosslinking (CXL) compared to MyoRing alone for the treatment of progressive keratoconus.


Methods: A total of 60 patients were enrolled in this randomized controlled trial. The patients were randomly allocated into two groups. In the first group, MyoRing was implanted, while in the second, it was inserted in the corneal stroma using the same technique, along with simultaneous CXL. Visual, refractive, topographic, and abberometric outcomes were measured preoperatively and at every postoperative visit.


Results: Data of 47 patients were available at the end of the study; 28 in the MyoRing group and 19 in the MyoRing + CXL group. The mean uncorrected distance visual acuity (UDVA) improved from 0.79 ± 0.39 logMAR to 0.52 ± 0.31 logMAR (P < 0.05) in the MyoRing + CXL group and from 0.65 ± 0.38 logMAR to 0.62 ± 0.23 logMAR (P = 0.70) in the MyoRing group. CDVA changed from 0.33 ± 0.19 logMAR to 0.25 ± 0.16 logMAR (P = 0.10) in the MyoRing + CXL group and 0.32 ± 0.22 logMAR to 0.33 ± 0.17 logMAR (P > 0.5) in the MyoRing group. The mean keratometry (Km) decreased from 47.5 ± 2.7 D to 43.8 ± 3.2 D (P < 0.001) in the MyoRing group and 49.3 ± 3.4 D to 45.1 ± 3.0 D (P < 0.001) in the MyoRing + CXL group. Besides, horizontal coma was significantly lower in the MyoRing + CXL group (P = 0.022).


Conclusion: MyoRing insertion combined with CXL is a safe and effective method for the treatment of keratoconus. The visual and topographic outcomes were comparable to that for MyoRing insertion after 10 months; however, horizontal coma was significantly lower in the MyoRing + CXL group.

Keywords:

CXL, Keratoconus, MyoRing

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