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Atum M, Alagöz G. Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Patients with RetinalArtery Occlusion. JOVR [Internet]. 2020Apr.6 [cited 2024Apr.18];15(2):195–200. Available from: https://knepublishing.com/index.php/JOVR/article/view/6737

https://doi.org/10.18502/jovr.v15i2.6737

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authors

  • Mahmut Atum

    Mahmut Atum

    Sakarya University Education and Research Hospital, Department of Ophthalmology, Adnan Menderes Caddesi Saglik Sokak, Sakarya, Turkey
  • Gürsoy Alagöz

    Gürsoy Alagöz

    Sakarya University Education and Research Hospital, Department of Ophthalmology, Adnan Menderes Caddesi Saglik Sokak, Sakarya, Turkey

Published Date

  • Apr 6, 2020
This journal is publishing all the articles under Creative Commons Attribution License CC BY 4.0.

Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Patients with RetinalArtery Occlusion

Journal of Ophthalmic and Vision Research (JOVR) / April–June 2020, Volume 15, Issue 2 / Pages 195–200

Abstract

Purpose: This study aimed to compare the neutrophil-to-lymphocyte (NLR) and plateletto- lymphocyte (PLR) ratios in patients with retinal artery occlusion (RAO) with those from a healthy control population and to identify the relationship between them.


Methods: Forty-six patients with RAO and fifty-one healthy control subjects were included in this retrospective case-control study. RAO was diagnosed following an ophthalmic examination and fluorescein angiography (FA). Blood neutrophil, lymphocyte, and platelet counts were recorded for each of the 97 subjects, from which NLR and PLR values were calculated.


Results: There were 46 patients (28 male [M], 18 female [F]) in the RAO group and 51 patients (27 M, 24 F) in the control group. No significant differences were found between patients with RAO and the control subjects in terms of gender and age (P > 0.05). Patients with RAO had significantly increased NLR values (2.85 ± 1.70) than the control subjects (1.63 ± 0.59, P < 0.001). The mean PLR in patients with RAO was 123.69 ± 64.98, while that in control subjects was 103.08 ± 36.95; there was no significant difference between the two groups (P = 0.055). A logistic regression analysis revealed that NLRs were 3.8 times higher in patients with RAO than in control subjects (odds ratio = 3.880; 95% confidence interval = 1.94 to 7.74; P < 0.001).


Conclusion: NLRs were significantly increased in patients with RAO compared to the control subjects.

Keywords:

Hemogram, Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, Retinal Artery Occlusion, Retinal Vessels

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