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Maryam Hosseini S, Dourandish M, Mazouchi M. Vogt-Koyanagi-Harada with Unilateral Clinical Presentation: A Case Report. JOVR [Internet]. 2020Feb.3 [cited 2024Jun.30];15(1):99–103. Available from: https://knepublishing.com/index.php/JOVR/article/view/5954

https://doi.org/10.18502/jovr.v15i1.5954

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  • Cited by 3 articles

authors

  • Seyedeh Maryam Hosseini

    Seyedeh Maryam Hosseini

    Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
  • Maryam Dourandish

    Maryam Dourandish

    Retina Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
  • Marjan Mazouchi

    Marjan Mazouchi

    Eye Research Center, Matini Eye Hospital, Kashan University of Medical Sciences, Kashan, Iran

Published Date

  • Feb 3, 2020
This journal is publishing all the articles under Creative Commons Attribution License CC BY 4.0.

Vogt-Koyanagi-Harada with Unilateral Clinical Presentation: A Case Report

Journal of Ophthalmic and Vision Research (JOVR) / January–March 2020, Volume 15, Issue 1 / Pages 99–103

Abstract

Purpose: To report a case of acute Vogt-Koyanagi-Harada (VKH) disease with unilateral clinical manifestations followed by late fellow eye involvement.


Case Report: This case report reviews the 12-month follow-up observation of a 44-year old woman who presented to the emergency department with unilateral progressive and painless visual blurring. Ophthalmoscopic findings, best-corrected visual acuity (BCVA), fluorescein angiography (FAG), enhanced-depth optical coherence tomography (EDIOCT), indocyanine green angiography, and response to treatment were evaluated. Her BCVA was 20/50 (logMAR: 0.4) in the right eye and 20/20 (logMAR: 0) in the left eye. Eye examination revealed optic disc swelling and multiple serous retinal detachments in the right eye and a normal left eye. She had headache, dysacusia, and mild hearing problems. Her past ocular and drug histories were unremarkable. Retinal imaging revealed characteristic features of VKH in the right eye. All laboratory testing results were inconclusive. VA and OCT findings significantly improved following the treatment with methylprednisolone 1 g/day continued by tapering dose of oral prednisolone. Two months after the presentation and during prednisolone tapering, VA of the left eye decreased and fundus examination revealed multiple serous retinal detachments in this eye.


Conclusion: Ophthalmologists should recognize unilateral and asymmetrical VKH disease with subtle systemic involvement.

Keywords:

Asymmetric VKH, Enhanced-Depth Optical Coherence Tomography, Indocyanine Green Angiography, Vogt-Koyanagi-Harada Disease (VKH)

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