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Torabi H, Saberi Isfeedvajani M, Ramezani M, Daryabari S-H. Choroidal Thickness and Hemoglobin A1c Levels in Patients with Type 2 Diabetes Mellitus. JOVR [Internet]. 2019Jul.18 [cited 2024Apr.23];14(3):285–290. Available from: https://knepublishing.com/index.php/JOVR/article/view/4784

https://doi.org/10.18502/jovr.v14i3.4784

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  • Cited by 9 articles

authors

  • Hamidreza Torabi

    Hamidreza Torabi

    Health Management Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
  • Mohsen Saberi Isfeedvajani

    Mohsen Saberi Isfeedvajani

    Medicine, Quran and Hadith Research Center and Department of Community Medicine, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran
  • Majid Ramezani

    Majid Ramezani

    Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
  • Seyed-Hashem Daryabari

    Seyed-Hashem Daryabari

    Health Management Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

Published Date

  • Jul 18, 2019
This journal is publishing all the articles under Creative Commons Attribution License CC BY 4.0.

Choroidal Thickness and Hemoglobin A1c Levels in Patients with Type 2 Diabetes Mellitus

Journal of Ophthalmic and Vision Research (JOVR) / July–September 2019, Volume 14, Issue 3 / Pages 285–290

Abstract

Purpose: The aim of this study was to assess the correlation of hemoglobin A1c (HbA1c) levels with choroidal thickness in patients with type 2 diabetes mellitus (DM) using spectral domain optical coherence tomography (SD-OCT).


Methods: In this prospective case series, 180 eyes from 90 patients with type 2 DM were classified into three study groups based on HbA1c values: group 1 included patients with good glycemic control (HbA1c ≤ 7%), group 2 included patients with moderate glycemic control (HbA1c between 7% and 8%), and group 3 included patients with poor glycemic control (HbA1c ≥ 8%). Additionally, 50 eyes from 25 non-diabetic subjects were enrolled to group 4 as a control group. Sub-foveal, nasal, and temporal choroidal thickness were measured and compared.


Results: Mean central, nasal, and temporal choroidal thicknesses in diabetic patients (247.80, 238.63, and 239.30 μm) were significantly less than non-diabetic healthy subjects (277.56, 262.92, and 266.32 μm). Additionally, mean central, nasal, and temporal choroidal thickness values in group 4 (277.56, 262.92, and 266.32 μm) were significantly greater than the corresponding values in group 2 (248.34, 237.55, and 236.45 μm) and group 3 (239.81, 234.62, and 233.94 μm), but was not significantly different from corresponding values in group 1 (259.46, 246.12, and 251.00 μm).


Conclusion: HbA1c values have a significant correlation with choroidal thickness in diabetic patients, and better glycemic control with HbA1c ≤ 7% may prevent choroidal thinning.

Keywords:

Choroidal Thickness; Diabetes Mellitus; Diabetic Retinopathy; Enhanced Depth Imaging Optical Coherence Tomography; HbA1c

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