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Van Brummen A, Feng S, Li E, J. Amadi A, Jacobs S. A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma. JOVR [Internet]. 2023Feb.13 [cited 2024May3];18(1):130–134. Available from: https://knepublishing.com/index.php/JOVR/article/view/12733

https://doi.org/10.18502/jovr.v18i1.12733

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authors

  • Alexandra Van Brummen

    Alexandra Van Brummen

    Department of Ophthalmology, University of Washington, Seattle, WA, USA
  • Shu Feng

    Shu Feng

    Department of Ophthalmology, University of Washington, Seattle, WA, USA
  • Emily Li

    Emily Li

    Department of Ophthalmology, University of Washington, Seattle, WA, USA
  • Arash J. Amadi

    Arash J. Amadi

    Department of Ophthalmology, University of Washington, Seattle, WA, USA
  • Sarah Jacobs

    Sarah Jacobs

    Department of Ophthalmology, University of Alabama, Birmingham, AL, USA

Published Date

  • Feb 13, 2023
This journal is publishing all the articles under Creative Commons Attribution License CC BY 4.0.

A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma

Journal of Ophthalmic and Vision Research (JOVR) / Jan–Mar 2023, Volume 18, Issue 1 / Pages 130–134

Abstract

Purpose: To demonstrate novel treatments for patients with high juvenile xanthogranuloma ( JXG) eyelid lesion burden.
Case Report: A 14-year-old girl was referred to the oculoplastic surgery service for management of worsening extensive bilateral eyelid and adnexal lesions in the setting of JXG. The patient underwent intra-lesional steroid injections, serial excisions, and reconstruction with skin grafts. She was subsequently treated with CO2 laser-assisted topical steroid application, which resulted in lesion regression.
Conclusion: A novel multimodal approach to treatment of severe periocular JXG, incorporating surgical debulking, skin autograft, CO2 laser, and intra-lesional steroids, can be effective for lesion control.

Keywords:

CO2 Laser, Juvenile Xanthogranuloma, Laser-assisted Steroid Delivery

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