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El Mokh H, Ben Yahia N, Bouziri M, Gattoufi W, Khabir A. Ciliary Body Schwannoma: A Case Report and Review of Literature. JOVR [Internet]. 2022Nov.24 [cited 2024Apr.19];17(4):581–586. Available from: https://knepublishing.com/index.php/JOVR/article/view/12339

https://doi.org/10.18502/jovr.v17i4.12339

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authors

  • Haythem El Mokh

    Haythem El Mokh

    Department of Pathology, Habib Bourguiba University Hospital, Medenine, Tunisia
  • Néjib Ben Yahia

    Néjib Ben Yahia

    Private Laboratory of Pathology, Houmt Souk Djerba, Tunisia
  • Mustapha Bouziri

    Mustapha Bouziri

    Ophthalmologist, Houmt Souk Djerba, Tunisia
  • Walid Gattoufi

    Walid Gattoufi

    Department of Pathology, Habib Bourguiba University Hospital, Medenine, Tunisia
  • Abdelmajid Khabir

    Abdelmajid Khabir

    Department of Pathology, Habib Bourguiba University Hospital, Medenine, Tunisia

Published Date

  • Nov 24, 2022
This journal is publishing all the articles under Creative Commons Attribution License CC BY 4.0.

Ciliary Body Schwannoma: A Case Report and Review of Literature

Journal of Ophthalmic and Vision Research (JOVR) / Oct–Dec 2022, Volume 17, Issue 4 / Pages 581–586

Abstract

Purpose: To present a case of intraocular schwannoma arising from the ciliary body with description of histological and immunophenotypic characteristics.


Case Report: A 32-year-old woman who was followed for glaucoma of the left eye and chronic renal failure at the stage of hemodialysis presented with buphthalmos and two weeks of blurry vision of the left eye. A magnetic resonance imaging exam was performed suspecting melanoma. Enucleation was rapidly performed. The histological examination after HE (Hematoxylin and Eiosin) and HEA50 (Hematoxylin and polychromatic solution EA 50) staining showed proliferation of mesenchymal monomorphic fusiform cells with eosinophilic cytoplasm and small oval nuclei which showed a tendency toward palisading. Some parts of the tumor were hypercellular with a fascicular arrangement (Antoni A pattern); other parts were weakly cellular with a myxoid arrangement (Antoni B pattern). Several Verocay bodies and a lot of hemorrhagic suffusions were described. Mitotic figures were very rare. Immunohistochemistry staining showed that tumor cells were positive for PS100 and vimentin.


Conclusion: Although ciliary body schwannoma is extremely rare, it should be considered in the differential diagnosis of intraocular tumors.

Keywords:

Antoni A and B Patterns, Ciliary Body, Local Excision, Schwannoma

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