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Esposti G, Luigi Esposti P, Costantino F, Zappalà D, Pinna A, Fruschelli M. Subthreshold Micropulse Laser for Long-Lasting Submacular Fluid after Rhegmatogeous Retinal Detachment Surgery. JOVR [Internet]. 2022Aug.9 [cited 2024Apr.19];17(3):390–396. Available from: https://knepublishing.com/index.php/JOVR/article/view/11577

https://doi.org/10.18502/jovr.v17i3.11577

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authors

  • Giulia Esposti

    Giulia Esposti

    Studio Oculistico Esposti, Siena, Italy
  • Pier Luigi Esposti

    Pier Luigi Esposti

    Studio Oculistico Esposti, Siena, Italy
  • Francesco Costantino

    Francesco Costantino

    Graduate School of Ophthalmology, University of Siena, Siena, Italy
  • Dario Zappalà

    Dario Zappalà

    Graduate School of Ophthalmology, University of Siena, Siena, Italy
  • Antonio Pinna

    Antonio Pinna

    Department of Medical, Surgical, and Experimental Sciences, Ophthalmology Unit, University of Sassari, Sassari, Italy
  • Mario Fruschelli

    Mario Fruschelli

    Dipartimento di Scienze Mediche Chirurgiche e Neuroscienze, University of Siena, Siena, Italy

Published Date

  • Aug 9, 2022
This journal is publishing all the articles under Creative Commons Attribution License CC BY 4.0.

Subthreshold Micropulse Laser for Long-Lasting Submacular Fluid after Rhegmatogeous Retinal Detachment Surgery

Journal of Ophthalmic and Vision Research (JOVR) / July–Sep 2022, Volume 17, Issue 3 / Pages 390–396

Abstract

Purpose: To assess the safety and efficacy of subthreshold micropulse laser (SML) photo-stimulation in the management of persistent subfoveal fluid (PSF) after surgery for rhegmatogenous retinal detachment (RRD).


Methods: In this pilot study, 11 eyes of 11 patients (8 men, 3 women) with long-lasting (12–18 months) PSF after surgery for RRD were evaluated before and after photostimulation with subthreshold micropulse yellow laser. Ophthalmic examination included best-corrected visual acuity (BCVA), Amsler grid test, ophthalmoscopy, autofluorescence (AF), and optical coherence tomography (OCT) with measurement of central point foveal thickness (CPFT). Primary outcome was subfoveal fluid resolution and secondary outcome was BCVA improvement.


Results: The mean CPFT and BCVA were, respectively, 436.8 ± 28.8 μm and 0.25 ± 0.1 μm decimal equivalent (DE) before photostimulation and 278 ± 54.4 μm and 0.57 ± 0.2 μm DE after photostimulation, a statistically significant difference (P < 0.001). Nine (81.8%) eyes showed improved BCVA, disappearance of macular detachment on ophthalmoscopy, reduced retinal pigment epithelium distress on AF, and restored macular profile with no neuroretinal alterations on OCT scans.


Conclusion: Although PSF after RRD surgery is often a self-limiting disease, our results suggest that SML photostimulation may be effective and safe in patients with clinically significant long-lasting PSF. Larger case–control studies are necessary to confirm these results.

Keywords:

Optical Coherence Tomography, Retinal Pigment Epithelium, Rhegmatogenous Retinal Detachment, Subretinal Fluid, Subthreshold Micropulse Laser

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