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Salouti R, Khosravi A, Fardaei M, Zamani M, Nejabat M, Ghoreyshi M, Salouti K, Nowroozzadeh MH. Inferior Spear-like Lens Opacity as a Sign of Keratoconus. JOVR [Internet]. 2022Jan.21 [cited 2024Apr.23];17(1):12–18. Available from: https://knepublishing.com/index.php/JOVR/article/view/10165

https://doi.org/10.18502/jovr.v17i1.10165

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authors

  • Ramin Salouti

    Ramin Salouti

    Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
  • Amir Khosravi

    Amir Khosravi

    Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
  • Majid Fardaei

    Majid Fardaei

    Department of Medical Genetics, Shiraz University of Medical Sciences, Shiraz, Iran
  • Mohammad Zamani

    Mohammad Zamani

    Salouti Cornea Research Center, Salouti Eye Clinic, Shiraz, Iran
  • Mahmoud Nejabat

    Mahmoud Nejabat

    Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
  • Maryam Ghoreyshi

    Maryam Ghoreyshi

    Salouti Cornea Research Center, Salouti Eye Clinic, Shiraz, Iran
  • Kia Salouti

    Kia Salouti

    Iran
  • M. Hossein Nowroozzadeh

    M. Hossein Nowroozzadeh

    Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
    https://orcid.org/0000-0002-7412-1900

Published Date

  • Jan 21, 2022
This journal is publishing all the articles under Creative Commons Attribution License CC BY 4.0.

Inferior Spear-like Lens Opacity as a Sign of Keratoconus

Journal of Ophthalmic and Vision Research (JOVR) / January–March 2022, Volume 17, Issue 1 / Pages 12–18

Abstract

Purpose: To report 21 cases of typical inferior feather-shape lens opacity associated with keratoconus.


Methods: In this cross-sectional study, we evaluated the association of keratoconus with inferior feather-shape lens opacity in refractive surgery candidates. Visual acuity, demographic, refractive, and topographic characteristics of 26 eyes of 21 patients with inferior feather-shape lens opacity were evaluated in detail. Pedigree analysis was also performed to assess possible inheritance.


Results: Overall, 2122 out of 33,368 cases (6.4%) without lens opacity had keratoconus, while 20 out of 21 patients (95.2%) with peculiar lens opacity had definite keratoconus (P < 0.001). Lens opacity was bilateral in 5 cases (24%), and keratoconus was bilateral in all 20 patients with lens opacity. Nine eyes out of thirty-six with a complete data record (25%) had severe keratoconus and underwent deep lamellar keratoplasty, while 11 (31%) had forme fruste keratoconus. Pedigrees were drawn for eight patients, most families of whom suggested an X-linked recessive inheritance.


Conclusion: The present study was the first to investigate patients with a peculiar inferior feather-shape lens opacity accompanied by bilateral keratoconus, which was observed in 95% of the patients. This finding should raise awareness as to the possibility of diagnosing keratoconus in the eyes of the patients with these characteristics.

Keywords:

Cataract, Feather-shape, Keratoconus, Lens opacity, Sectoral

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