TY - JOUR AU - Najem Aldin Mohammed Osman AU - Intisar Elhag Elraya AU - Yassir Mahgoub Mohamed AU - Muataz Mohamed Eldirdery AU - Salaheldein Gumaa Elzaki AU - Abdallah Elssir Ahmed AU - Ali Mohamed Elhassan Eleragi PY - 2018/12/26 Y2 - 2024/03/29 TI - Frequency of Methicillin Resistance among Staphylococcus aureus Clinical Isolates in Khartoum State, Sudan JF - Sudan Journal of Medical Sciences (SJMS) JA - Sudan JMS VL - 13 IS - 4 SE - Original Research Article DO - 10.18502/sjms.v13i4.3596 UR - https://knepublishing.com/index.php/SJMS/article/view/3596 AB - Background: Methicillin-resistant Staphylococcus aureus (MRSA) have emerged as an important cause of nosocomial and community-acquired infections ranging from mild to severe life-threatening infections. Therefore, a reliable detection of such strains is required for effective treatment. Objectives: To determine the frequency and the antibiogram of MRSA among different clinical isolates. Study Design: A cross-sectional, descriptive study. Materials and Methods: Standard bacteriological methods, disk diffusion and PCRwere performed to determine the frequency of MRSA among different clinical isolates. Results: The overall results showed 96/210 (45.7%) of isolates were MRSA mostly recovered from wounds and blood stream. High percentage was detected in hospitalassociated (HA) strains (64.2%) rather than community (CA) (37.1%) (P-value < 0.001). From the generated Antibiogram, Co-trimoxazole was the most active (80.2%), while Penicillin was the least one (6.2%). Conclusion: As MRSA strains were mostly isolated from Hospitals, clinicians should beaware of such burden strains. Local frequency investigation of MRSA is recommended for perfect diagnosis and treatment. ER -