KnE Life Sciences | The 1st Payung Negeri International Health Conference | pages: 16–26


1. Introduction

Diabetes Mellitus (DM)is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Diabetes Mellitus is classified into 4 types namely DM type1 (absolute insulin deficiency), DM type 2 (non-insulin-dependent diabetes), gestational DM and other specific types of DM. Non-insulin-dependent diabetes (DM type 2) is the most common form of diabetes, which accounts for 85 - 95% of those aged 40-59 years old. People with diabetes are highly vulnerable of having wound, especially at feet. The wound in this Diabetes Mellitus is chronic and usually hard to cure.A study in United States shown that 75% of diabetic people get health problem on their feet while 44% of them must get medical treatment [1,5,19].

Diabetes Mellitus is a chronic disease which fastens the atherosclerosis and according to some researches, is the main cause of PeripheralArterialDisease(P.A.D). Peripheral Arterial Disease is a disease in which plaque builds up in the arteries that carry blood to your head, organs, and limbs. Therefore theperipheral blood perfusion will be limited. This is also one of the causes of diabetic wounds on the patients with diabetes Mellitus type 2. Peripheral arteries that are often disrupted are the tibial artery and peroneal artery or fibular artery, especially the area between the knee and leg joint [3,16].

Some researches found that a non-invasive examination to evaluate P.A.D and recommended for the patients of diabetes mellitus older than 50 years old is known as Ankle Brachial Index (A.B.I) test. The normal score of A.B.I is 0.9 -1.3, in which the value lower than 0.9 is categorized as abnormal and when the score is higher than 1.3is the sign of classification on the blood vessels, therefore the result of A.B.I test can be used to diagnose P.A.D. The lower A.B.I score means higher risk of vascular disease [8, 12]. At that time, the patients usually have claudication complaints (pain in the extremities). On the other hand, when the ABI index is lower than 0.5, the patients usually have claudication when they take rest. As of 2015, an estimated 415 million people had diabetes worldwide,and there will be 642 million people with diabetes in 2040. The numbers of diabetes patients in Indonesia is the seventh with 10.2 million people and will significantly increase into 21.3 million in 2040. The data recorded that there are 422 million diabetes people in 2016 and 1.5 million people die due to diabetes mellitus[7,18,19]. Santa Maria Hospital aa one of the biggest hospitals in Pekanbaru also recorded the inceasing number of diabetes mellitus patients both inpatiens and outpatients.

Figure 1

Sources: The Data of Medical Records at Santa Maria Hospital Pekanbaru.


Based on the interview with the nursing management of Santa Maria Hospital, it can be concluded thatthere is no standard procedure of ABI test for patient of diabetes mellitus and in general the nurses of the hospital do not know how to conduct the ABI test. In fact, the knowledge on how assesing the ABI in order to detect the PAD earlier as one of a risk factor of diabetic wound is important as the number of diabetes mellitus patients increased. Based on that preliminary observation, the researcher is interested in conducting a research on the correlation of Ankle Brachial Index to the risk of deabetic wound on Diabetes Mellitus type 2 patients at Santa Maria Hospital Pekanbaru.

2. Methods and Equipment

This is a quantitative research using cross sectional design. The data collected by observation onmeasuring of systolic blood pressure on both extremities in the brachial and ankle areas of the inpatiens of Diabetes Mellitus type 2 and conducting anamnesa on the symptoms of PAD at Santa Maria Hospital. The sampling technique is using consecutive sampling method. The inclusion criteria is the diabetes mellitus patients with no diabetic wound, while the exclusion criteria is the diabetes patients with extrimity edema, have D.V.T disease and breathless that can not lay down in 5-10 minutes. The research instrument is using the vascular doppler 5 Mhz. The measurement was carried outon both ankles and brachials. The results of ABI measurements were that blood pressure in the cystole ankle was divided into systole brachial blood pressure. Diabetic patientshave a risk of diabetic injury if the ABI value is abnormal and there is one symptom of PAD. Patients who are not at risk of experiencing ulcers if the value of ABI isnormal and no signs of PAD were found. The symptoms of PAD are claudication, resting time pain, history of scarred wounds, dorsalis pedis pulse or tibial penosterior were not palpable or weak, legs looked pale, and cool feet. Data analysis on this research used the Chi Square test to test the level of statistical significance between the value of the brachial index and the risk of diabetes wound in patients with type 2 diabetes mellitus.

3. Result

Based on the results of the research, it was found that most of type 2 Diabetes Mellitus patients were suffered by patients aged 45-54 years and aged 55-64 years respectively as 29.1%. The third Diabetes Mellituspatients based on the results of the research were 65-74 years old as much as 18.2%. patients with an age range of 15-24 years and 25-34 years old are the smallest number of DM patients, which are 1.8%. This is consistent with the International Diabetes Federation (IDF) report that the number of Diabetes Mellitus patients increased at the age of 19-74 years and the age group 70-74 years had a higher incidence of 19.4% followed by the age group 55-59 years (Huang et al., 2015). According to WHO (2016) as the age increased,the ability of tissues to take blood glucose decreases and usually happened on patients over the age of 40 years.

There were 55 respondents with a total of female respondents was 52.7% and men 47.3%, female and male ratios 1.1:1. Other research conductedby Osei et al ((2013) in America found the ratio of women with diabetes mellitus and men was 2:1, while research by Choi et al (2014) in South Korea found the ratio diabetes mellitus onmale to female 2:1. Based on the educational background of patients, most of patients with type 2 diabetes mellitusat Santa Maria Hospital were the respondents with secondary education level, namely junior high school and high school that was as much as 43.6%. Respondents with lower education as much as 32.7% and higher education as much as 23.7%. In the case of diabetes mellitus patients education is not a risk factor, but education will be useful when someone has been affected by diabetes mellitus. The educational background will help the patient in managing and implementing ways to prevent DM complications and maintain blood sugar stability. Most of the patients have the type 2 diabetes mellotus for 1-5 years, which is 38.2% and then < 1 year is 29.1%. From these results we can conclude that many patients newly diagnosed with type 2 diabetes mellitus. This is in accordance with what was revealed by the International Diabetes Ferderation (IDF) in 2015 world DM sufferers continue to increase every year, 2015 amounting to 415 million people and estimated to increase to around 642 million people with DM in 2040. The World Health Organization (WHO, 2017) stated that the number of DM patients in 2017 is 422 million. IDF in 2015 explained the main complications of diabetes are attacking organs such as the eyes, oral health, heart, kidneys, nervous system and causing diabetic wounds. From the results of the study patients with type 2 DM in Santa Maria Hospital had the most comorbidities, hypertension as much as 16.7%, stroke infarction 12.7% and TB 9.09%.According to WHO the diagnosis of DM patients if the patient experiences classic DM symptoms namely polyuri, poliphagi, polydispi and has GDS > 200 mg / dl or GDP > 126 mg / dl, or GDPP > 200 mg / dl. From the results of the study of DM patients who measured ABI GDS measurement results > 200 mg / dl as much as 54.5% and the rest had GDS < 200 mg / dl as much as 45.5%. Based on the results of the research on55 respondents, 70.9% of the results of normal ABI measurements were 0.91 1.3, the results of ABI with mild occlusion were 0.7-0.9 as much as 23.6% and the remaining 5.5% ABI values > 1.3 or experiencing blood vessel calcification. Based on male sex respondents as many as 26 patients who had normal ABI 76.95, mild occlusion 19.2% and vascular calcification 3.8%, while female respondents as many as 29 patients had normal ABI 65.5%, mild ABI occlusion 27.6% and ABI with vascular calcification 6.9%.

Based on the results above, it can be seen that women have more abnormal ABI than men, both in mild occlusion and in blood vessel calcification. The comparison is 1.3:1. The research conducted by Pratomo (2014) in Lampung, concluded of 98 type 2 DM patients with 22.5% ABI abnormalities also found that the abnormal ABI ratio of Bordeline ABI in Type 2 DM patients between women and men was 1.3:1 Najla et al. research In 2016 in Pontianak, the results of 80 respondents found Abi abnormal value was higher than the normal ABI, which was as much as 51.25% while the normal one was 48.75%. (After this is lot of graphics)

Table 1

Distribution of Respondents Based on ABI Value and Wound Risk of Type 2 DM Patients at Santa Maria Hospital.

Wound Risks ABI Scores No Symptoms of PAD There is Symptom of PAD Total P value
ABI Normal (0.91-1.3) 35 89.7 % 4 10.3 % 39 100% 0.000
Mild Occlusion (0.7-0.9) 0 0% 13 100% 13 100%
Blood vessel classification (ABI > 1.3) 0 0% 3 100% 3 100%
Total 35 63.6% 20 36.40% 55 100%
Source: Results of the 2018 study

Based on the results of the Chi Square bivariate analysis with Pearson Chi Sguare is obtained (P = 0,000 < α: 0,05) that H0 is rejected, it can be concluded that there is a significant relationship between ABI and the risk of diabetic wound. Based on the definition of operational risk of wound is when patients with type 2 DM with ABI values are ABI < 0.9 and ABI > 1.3 and have one symptom of peripheral arterial disease (PAD). Symptoms of PAD according to the American Association Heart (AHA) are cheating, pain at rest, history of injury which is difficult to heal, nadidorsalis pedis or posterior tibialist is not palpable or weak, pale and cold on the legs [3]. According to the research of the United Kingdom Prospective Diabetes Study (UKPDS) DMtype 2 patients are at risk of developing PAD compared to general patients. Every 1% increase in HbA1C, there is a 28% risk of experiencing PAD. The results of the study on 55 respondents, 70.9% were not at risk of experiencing diabetic wounds and 29.1% of patients who had a risk of experiencing diabetic wounds [12].

4. Conclusion

Research on the correlation of ABI to the risk of diabetic wounds in type 2 DM patients at Santa Maria Pekanbaru Hospital can be concluded with the results of ABI measurements from 55 respondents obtained results 70.9% of patients had normal ABI values and 23.6% mild occlusion and the remaining 5.5 % experienced calcification of blood vessels with ABI values > 1.3. The risk of diabetic wound is measured by two indicators, namely the ABI value < 0.9 and there is one or more PAD signs. The results showed that 70.9% were not at risk of developing diabetic wounds and 29.1% of patients who had a risk of developing diabetic wounds. Based on the Chi Square statistical test there is a significant correlation between the value of ABI and the risk of injury in type 2 DM patients at the Santa Maria Hospital in Pekanbaru with a P value = 0,000 < 0.05.

Hospitals are expected to conduct ABI measurements well as a standard procedure for diabetic patients to detect early symptoms of PAD and risk of diabetic wounds. For further research it is recommended to conduct research on ways or techniques to keep ABI values within normal limits.


This research was supported by the researchers and Nurses of Santa Maria Hospital Pekanbaru Riau Indonesia.


The researcher would like to thank Payung Negeri Institute of Health and Santa Maria Hospital Pekanbaru for their contribution and support to the research. The researcher is also thankful to the reviewers who gave their valuable inputs to the manuscript and helped in completing the paper.

Conflict of Interest

The researcher has no conflict of interest to declare.



American Diabetes Association (ADA). (2017). Standards of Medical Care in Diabetes 2017.


Choi dan Jeon SB.(2014). Predictive factors for successful limb salvage surgery in diabetic foot patients, 14:113. Retrieved from 1471-%0A2482/14/113.%0A. Diakses 10 Juni 2017.


Gerhard Herman, (2016). AHA/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.


Journal of the American College of Cardiology, 69(11), 1465–1508. 16.11.008


Gitarja, W. S. (2008). Perawatan Luka Diabetes. (T. W. Publishing, Ed.) (Seri Peraw). Bogor: WOCARE INDONESIA.


Huang, Y., Ogurtsova, K., Fernandes, R., Cavan, D., Makaroff, L. E., Shaw, J., & Cho, N. H. (2015). IDF Diabetes Atlas Estimates for the Global Diabetes Prevalence of Adults Aged 18 to 99 years, (1671), 1671.


International Diabetes Federation (IDF). (2011). IDF Diabetes Atlas Fifth edition. (online) files/ EN_6E_Atlas_Full_pdf, diakses 30 Oktober 2017.


Kirsner, M. F. (2010). The Standard of Care for Evaluation and Treadment of Diabetic Foot Ulcers.


Osei D, Brechow A, Slesaczeck T, Münch D, Nanning T, Paetzold H, et al. (2013). Improving major amputation rates in the multicomplex diabetic foot patient focus on the severity of peripheral arterial disease;4(3):83-94.


PERKENI. (2015). Pencegahan dan pengelolaan Diabetes Melitus Tipe 2 di Indonesia, (Online) Final.pdf. diakses 30 Oktober2017.


Potier, L., Khalil, C. A., Mohammedi, K., & Roussel, R. (2011). Use and Utility of Ankle Brachial Index in Patients with Diabetes. European Journal of Vascular & Endovascular Surgery, 41(1), 110–116. 10.09.020


Pratomo, I. B. (2014). Gambaran ABI Penderita DM tipe 2 di Puskesmas Kotabumi II Kabupaten Lampung Utara tahun 2014, 1–37.


Rekam Medis. RS Santa Maria 2016. Pekanbaru.


Riset Kesehatan Dasar, (2013). Penelitian & Pengembangan.(online).www.d Diakses 10 Agustus 2017.


Standards of Medical Care in Diabetes (2017), American Diabetes Asosiation (ADA). 40(January).


Resnick, H. E., Lindsay, R. S.,Mcdermott, M. M., Devereux, R. B., Jones, K. L., Fabsitz, R. R., & Howard, B. V. (2014). Relationship of High and Low Ankle Brachial Index to AllCause and Cardiovascular Disease Mortality. 0000112642.63927.54


Standards of Medical Care in Diabetes (2017), American Diabetes Asosiation (ADA). 40(January).


World Health Organization (WHO). (2016a). Diabetes Magazine is on the Rise 3.7, 1–2. (Januari 2016)


World Health Organization (WHO). (2016). Global Report on Diabetes. Diakses 1 September 2017.


Yuliani, F., Oenzil, F., & Iryani, D. (2014). Artikel Penelitian Hubungan Berbagai Faktor Risiko Terhadap Kejadian Penyakit Jantung Koroner Pada Penderita Diabetes Melitus Tipe 2, 3(1), 37–40.



  • Downloads 5
  • Views 39



ISSN: 2413-0877