THE EFFECT OF SUPPLEMENTATION PROBIOTIC <i>Lactobacillus casei</i> STRAIN Shirota L AGAINST COLONIZATION OF <i>Staphylococcus aureus</i> Nasal Swab ISOLATES FROM PATIENTS WITH ALLERGIC RHINITIS
Abstract
Staphylococcus aureus is the most important type of bacteria causing infections in humans. There are several potential factors for Staphylococcus aureus nasal careers in healthy adults, i.e. chronic sinusitis, the long-term skin trauma, respiratory allergies, asthma, allergen injection therapy. Probiotics are life microorganisms which have a positive effect on prevention or treatment of certain disease conditions when consumed. Manipulation of intestinal flora with probiotics for the prevention and treatment of rhinitis allergy should be developed. This study aims to determine the effect of supplementation probiotic Lactobacillus casei Shirota strain against colonization Staphylococcus aureus nasal swab isolates from patients with allergic rhinitis.
This research was quasi-experimental case-control design with a control group pretest-postest design. The study was conducted at the Microbiology and Research Laboratory School of Medicine Muhammadiyah Yogyakarta University, on February-July 2011. Fourty two students school of medicine Muhammadiyah Yogyakarta University, with the inclusion criteria suspect allergic rhinitis based on history. Volunteers who have a history of allergic rhinitis were taken nasal swab to check the number of S.aureus bacteria. Volunters consumed milk containing Lactobacillus casei strain Shirota daily for a month, then taken to be examined nasal swab S.aureus bacteria numbers.
The results showed that the average number of bacteria nasal swab isolates before supplementation about 92 CFU. After given the probiotic Lactobacillus casei Shirota strain during a month, the average number of S.aureus about 27 CFU. It can be concluded that supplementation with Lactobacillus casei strain Shirota probiotics can reduce Staphylococcus aureus colonization in patients with allergic rhinitis.
Keywords: Staphylococcus aureus, Lactobacillus casei, allergic rhinitis
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