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Gunther, S., Dambaev, G., Kang, J., & Gunther, V. (2017). The Device for the Treatment of Diabetes with Use of Infrared Radiation and Porous TiNi Based Alloy. KnE Materials Science, 2(1), 159-167. https://doi.org/10.18502/kms.v2i1.792

https://doi.org/10.18502/kms.v2i1.792

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authors

  • S.V. Gunther
    No author data available.
  • G.Ts. Dambaev
    No author data available.
  • J.H Kang
    No author data available.
  • V.E. Gunther
    No author data available.

Published Date

  • Jul 17, 2017

The Device for the Treatment of Diabetes with Use of Infrared Radiation and Porous TiNi Based Alloy

KnE Materials Science / Shape Memory Biomaterials and Implants in Medicine (SMBIM) / Pages 159-167

Abstract

The research addresses the problem of design and development of a new needle-free method for diabetes treatment. New porous-permeable TiNi-based materials and new methods of IR-radiation effect on tissues of the body have been used in the research. The properties of porous alloys are similar to those of high-capacity materials that can hold a large volume of insulin solution in the porous structure of the material. With this, IR-radiation stimulates directed diffusion of insulin from the porous TiNi structure to the tissues of the body. This makes the basis for development of a needle-free device for diabetes treatment. The proposed technique does not cause skin irritation, and it is safe when used in practice. The efficiency of insulin delivery was evaluated in clinical studies. The results showed the potential of prolonged delivery for both insulin and other liquids.

References
[1]V.E. Gunther, G.Ts. Dambaev, P.G. Sysoliatin et al., Delay Law and New Class of Materials andImplants in Medicine, Northampton. MA: STT. 2000.


[2]Gunther, S.V.; Dambaev, G.Ts.; Starchenkov, D.D. Patent RF RU2534521 [in Russian]. 2012.


[3]Gunther S.V., Dambaev G.TS., Chekalkin T.L., Kang J-H, Kim J.S., Gunther V.E. / Porous TiNi-based material and infrared radiation in needle-free treatment of diabetic patients //Advanced Materials Letters 2016, 7 (9), 713-718.


[4]Gunther S.; Kokorev O.; Chekalkin T.; et al.; Adv. Mater. Lett., 2015, 6(9), 774DOI:10.5185/amlett.2015.5882


[5]Bergenstal, R.M.; Strock, E.S.; Peremislov, D.; et al.; Mayo ClinProc.,2015, 90, 329. DOI:10.1016/j.mayocp.2014.12.014


[6]Gunther S.V., Dambaev G.Ts. The needleless insulin delivery unit in diabetes with the use ofinfrared radiation/ International Conference “Global Science and Innovation”. Materials ofthe VII international conference. Chicago, USA 2016, Page 260-267.