TY - JOUR AU - S G Anaskin AU - A P Vlasov AU - M A Spirina AU - P P Zaytsev AU - T I Vlasova AU - I D Korniletskiy AU - D E Timoshkin AU - V S Geraskin AU - E A Komochkina PY - 2018/04/17 Y2 - 2024/03/29 TI - Laser Therapy in Correction of Optimization of Surgical Endointoxication JF - KnE Energy JA - KEn VL - 3 IS - 2 SE - Articles DO - 10.18502/ken.v3i2.1786 UR - https://knepublishing.com/index.php/KnE-Energy/article/view/1786 AB - The problem of endointoxication remains one of the most urgent in modern surgery. The severity of the intoxication syndrome is determined not only by the intensity of the entry of toxic substances into the bloodstream from the lesion focus, but also by the adequacy of the functioning of the main mechanisms of detoxification - elimination of toxins. Clinical and laboratory studies of 62 patients with acute peritonitis were performed. To this end, daily sessions of laser therapy with “Matrix” were conducted for 5 days after the operation, using a head of KLO3 (radiation with a wavelength of 635 nm, 2 mW). Laser irradiation of blood through the skin in the projection of the ulnar vein was performed for 30 minutes. Using laser therapy for patients with acute peritonitis led to the reduction of the endogenous intoxication severity. The level of medium-mass molecules (λ = 280 nm) decreased by 13.3-26.2% compared to the control, the level of average-weight molecules (λ = 254 nm) decreased by 15.5-32.6% (p <0.05) against the background of laser therapy. Thus, the use of laser therapy in patients with acute peritonitis has led to a decrease in the severity of endogenous intoxication. One of the significant components of this treatment is its ability to improve microcirculation and, as a result, to correct lipid peroxidation and hypoxia, which reduces catabolic phenomena (one of the sources of endogenous intoxication). Clinical and laboratory studies have established that the effectiveness of such treatment decreases with severe forms of peritonitis. ER -