As part of the submission process, authors are required to check off their submission's compliance with all of the following items, and submissions may be returned to authors that do not adhere to these guidelines.

• As part of the submission process, authors are required to check off their submission's compliance with all of the following items, and submissions may be returned to authors that do not adhere to these guidelines.
  On behalf of all the contributors, I certify that we have participated sufficiently in the intellectual content, conception and design of this work or the analysis and interpretation of the data (when applicable), as well as the writing of the manuscript, to take public responsibility for it and have agreed to have our name listed as a contributor.
  We believe the manuscript represents valid work. Neither this manuscript nor one with substantially similar content under our authorship has been published or is being considered for publication elsewhere, except as described in the covering letter.
  We certify that all the data collected during the study is presented in this manuscript and no data from the study has been or will be published separately.
  We attest that, if requested by the editors, we will provide the data/information or will cooperate fully in obtaining and providing the data/information on which the manuscript is based, for examination by the editors or their assignees.
  Financial interests, direct or indirect, that exist or may be perceived to exist for individual contributors in connection with the content of this paper have been disclosed in the cover letter. Sources of outside support of the project are named in the cover letter.
  All the contributors have given the rights to me, as the corresponding author, to make necessary changes as per the request of the journal, do the rest of the correspondence on our behalf and I will act as the guarantor for the manuscript on our behalf.
  All persons who have made substantial contributions to the work reported in the manuscript, but who are not contributors, are named in the Acknowledgment and have given us their written permission to be named. If we do not include an Acknowledgment that means we have not received substantial contributions from non-contributors and no contributor has been omitted.
• The manuscript was prepared according to the Instructions to Authors.
  
  
• I have downloaded the Title Page here and Main Text here and I will upload them as two separate documents in the next step.
  
  
• I will upload each figures (PNG/JPEG/TIFF) as separate documents in the next step.
• I have included the “Declarations” section in the title page.
• All contributors and their email addresses must be entered during the submission.
• I (corresponding author) confirm that all authors have met International Committee of Medical Journal Editors (ICMJE) recommended authorship criteria.
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  If the manuscript has been submitted to the preprint platform, the following information should be clearly disclosed:
  
  - The name of the platform, DOI, and the link should be clearly indicated.
  - Confirm that the preprint version has not been formally peer-reviewed.
  - Confirm that the preprint server that the preprint was published on will also link to the definitive version of the article to ensure that all readers can quickly and easily find the most recent, peer-reviewed version of the work.